InterWest Partners

InterWest Partners founded in 1979 is a venture capital firm based in Menlo Park California. The firm?s primary focus is providing venture capital to early-stage healthcare and information technology companies. The firm has raised 1 funds to date with over $2.8 billion in committed capital. The firm?s tenth fund closed in 29 at $65 million. The firm generally invests in the Series A and B rounds, initially allocating $8-12 million and up to $2 million over the life of the investment. The firm primarily invests in US-based companies but will also selectively consider opportunities abroad. The firm is actively seeking new investment opportunities.
Doug Fisher
Partner 

Ischemia Care United States

Ischemia Care (ISC) is a clinical stage, capital efficient, venture capital backed, diagnostic laboratory company commercializing ISCDX, a blood test for cause of ischemic stroke (including atrial fibrillation or “AF”), leading to timely diagnosis and treatment, resulting in hospital cost savings and improved patient outcomes. ISC is executing on the Biomarkers of Acute Stroke Etiology (BASE) study , clinicaltrials.gov identifier NCT02014896 to support clinical adoption as an LDT through a company owned CLIA laboratory. ISC's initial focus is on the 40% (320K annually) ischemic strokes which are diagnosed as unkown cause (or "cryptogenic") as these patients typically are undertreaked and at a high risk for recurrence.

Stroke is the third leading cause of death worldwide with 20M annual events. In the US, there are 800K strokes, of which 195K are recurrent. Despite advances in imaging, cardiac monitoring, patient history assessment, and clinical examination, in 40% of ischemic strokes, the cause is unknown (or “cryptogenic”) leading to high recurrence and death.  There are no blood tests for cause of stroke. The identification of cause will change outcomes per Stroke Guidelines by adoption of “cause based” treatment regimen to prevent a more massive, debilitating, and costly recurrence. For example, identifying “undetected” AF in cryptogenic patients provides a 60% risk recurrence reduction.

Website:
www.iscdx.com
Year Founded
2009
Biotech Subsector
Biotech Phase of Development
Medtech Phase of Development
Technology Overview
Blood test for cause of stroke. The test (called ISCDX) detects immune responses by RNA expression related to causes of stroke, including AF, within minutes of event. ISCDX is ordered by a clinician at a hospital after a stroke has occurred, a tube of blood is drawn, sent to the ISC CLIA laboratory, results are reported to the physician during patient hospitalization , and paid through the hospital under existing reimbursement (DRG) codes. ISCDX may reduce cost by $7,000 per patient and increase hospital revenue.
Alliance & Collaborations
Medronic, Affymetric, Cleveland Clinic, MUSC, Allegahany Health Network, Albert Einstein Medical Center, UCLA.
Supporting Metrics or Evidence
14+ years, 600+ patients of data, 5 patents, $5M Federal Funding (pre licensing by ISC), and publications in major peer reviewed journals. Previous research has demonstrated sensitivity/ specificity > 95%. ISC reached milestones faster and with less investment than comparable exits.
Current Financing Needs
ISC is raising a $5M series C at $6.5M pre money, with $2.5M closed. ISC previously raised $2.3M in equity and $1.4M in non dilutive funding, further demonstrating commercial and technical merit.
Current Timeline
ISC is following proven commercial pathway. The BASE clinical trial will serve as a final clinical validation and build sales channel to commercially offer the ISCDX test through the company CLIA laboratory. This strategy is similar to companies such as Veracyte and Foundation Medicine (both 2013 IPOs).
Current Investors
Broadview Ventures, Cleveland Clinic (GCIC grant), Queen City Angels, Ohio Third Frontier, Accelerant Fund, and private individuals.
IP Status
5 patents in various stages of prosecution, international filings as well.
Management Team Highlights
Proven management team and board (2 IPOs, multiple exits, past president of AHA, chief of cardiology at Stanford, 4 VC directors), KOLs in the field of stroke (including author of the Stroke Guidelines), strategic support (Affymetrix, Medtronics), and leading stroke center directors.
Jeff June
Jeff June
LinkedIn logo CEO & Founder 

Jump Capital United States

Jump Capital was founded in 2012 and is based in Chicago, with an additional office in San Francisco. The firm is investing from a $250m fund, and is interested in a variety of sectors including the life science field. For life science investments, Jump Capital typically allocates $2-15 million, and prefers to invest in Series B-C rounds. Jump Capital invests in the USA and Canada, and has previously invested in 6 healthcare companies.

Jump Capital invests in medical devices, diagnostics, digital and mobile health, and healthcare services. The firm is open to opportunities in any clinical indication. Jump Capital is only interested in devices and diagnostics that have in-human data.

Dr Garrett Vygantas
LinkedIn logo Partner 

JVC Investment Partners United States

JVC Investment Partners is a private investment firm that was founded in 2000 and is based in Chicago, Illinois. The firm focuses on investments in the healthcare industry. The investment size can vary greatly and is very flexible depending on each company’s needs. The firm provides venture capital and growth capital to healthcare companies. For early-stage investments, the firm targets companies that provide solutions for hospital acquired infections, medication errors, healthcare system operational efficiency enhancements and cost reductions, and chronic disease management, and it typically invests equity or convertible preferred equity in post series A rounds. For growth investments, the firm targets companies with compelling products and strong position in niche markets and with an EBITDA in excess of $2 million. The firm primarily invests in companies based in US.

David Jonas
Founder, President & CEO 
Jonathan Jonas
Partner 

Kineta United States

Kineta® is a nationally-recognized biotechnology company focused on developing leading edge therapeutics in three large high need therapeutic areas: autoimmune disease, viral disease and chronic pain. Our company is focused on the development of novel drug candidates each the outcome of years of scientific exploration and supported by an extensive body of peer-reviewed NIH-supported research.

Biotech Phase of Development
Technology Overview

Kineta® is developing a pipeline of next-generation medicines to respond to the needs of millions of people facing diseases around the world. Our scientific areas of expertise are immunology and neuropathic pain with research directed at curbing inflammation and returning the immune system to normal function. Kineta has five unique drug programs in development and each program represents a novel mechanism-of-action and has potential to result in a new class of drug. The innovative portfolio is derived from leading edge scientific research that taps into promising recently discovered cellular channels that control the body's defense mechanisms. Kineta’s drug programs are designed to enhance or modulate the natural human immune system and show great potential to be more effective, more tolerable and confer fewer side effects than existing drugs. We anticipate our products will be highly sought after by patients, healthcare providers and the pharmaceutical industry.

Alliance & Collaborations
27 Scientific and academic collaborations
Current Financing Needs

Series B round of $5M with follow on series C for an additional $20M.

Current Timeline

Autoimmune drug successfully completed phase I clinical trials and is currently in a phase 1B extension study to be completed 1st quarter.  In discussions with numerous large pharmaceutical and biotechnology companies around a licensing transaction.

Antiviral and pain programs are currently in pre-clinical development with high industry interest.  We are in significant partnering discussions around several of our anti-viral drug candidates.

Current Investors

We have raised $36M since 2008.  This has been augmented with an additional $52M in NIH funding.

Our current investors are accredited investors, high net worth individuals, Family Offices, a boutique PE group and the Iacocca Foundation.

IP Status
  Protected Pipeline Secured with a
Valuable IP Portfolio ØStrong IP across each development program ØProprietary expertise in innate immunity & autoimmunity Ø27 Patent Families (28 owned, 6 in-licensed) •45 Issued Patents •154 Pending country applications •7 Pre-nationalized PCT or provisional families
Management Team Highlights

Chuck Magness, PhD

CEO

Human Genome Project; Co-founded & Sold Illumigen Biosciences ($17M + 321M); Kineta Enterprise >$60M

Shawn Iadonato, PhD

CSO

Human Genome Project; Illumigen Biosciences; Grew 5 Kineta Programs; 1st Kv1.3 in Clinic; >$35M  R&D Funds

Craig Philips, MBA

Commercial Operations

 VP & GM, Schering Plough, VP & GM, Bayer, President & GM CTI

Blake Ilstrup, JD

General Counsel /

Corporate Dev.

Hundreds of transactions with Cooley and Venture Law Group, General Counsel of Qpass, 6 Kineta transactions

Rob Hedequist

Corporate Development

Major Accounts, Managed Care & Sales/ Marketing Pfizer and Amgen; National Director Schering–Plough

Dan Eramian

Corporate Communications

First VP of communications for Biotech Industry Organization; US DOJ Director of Public Affairs; SBA

Ken North

Corporate Development

Founding CEO Seattle Savings Bank; Past president Seattle Kiwanis, Chamber of Commerce; Seafair Commodores

Dan Burge, MD

Clinical

Trubion (CMO), VP Early Development Immunex, Amgen (early development on Enbrel)

Jeff Fellows

Regulatory

Global Regulatory Lead Amgen,  VP Regulatory Alder, VP Regulatory CTI,  First Kv1.3 in clinic, Sensipar Amgen

Mr Rob Hedequist
Senior Vice President Corporate Development 
Blake Ilstrup
Jacques Bouchy

Life Science Angels

Life Science Angels Inc was founded in 2004 and is based in Sunnyvale CA. The group makes early-stage equity investments in a wide range of life science companies. Life Science Angels invests primarily in California but is open to investing out of state provided a round is being syndicated with a local angel group. Life Science Angels does not rule out investing outside the USA but has yet to do so. The group invests as individuals and allocation sizes are therefore highly varied but are usually of about $2-$6, Life Science Angels usually invests in rounds seeking $3 million or less. The group is interested in syndicating rounds with other angel groups.

Investor Type
Biotech Phase of Development
Medtech Phase of Development
Capital Structure Preference
Investment Stage Preference
Dr Faz Bashi
Chair Digital Health & Sciences 
Karl Handelsman
Founder & Chairman 
Allan May
Founder 

Life Science Equity Partners

Life Science Equity Partners is a private equity firm based in Palo Alto California. The firm is solely focused on life science investments. The firm will invest in companies at all stages including early-stage companies with products still in development and late-stage companies with revenue. The firm typically makes early stage investments with a 1 year exit strategy in mind. The investment size is highly variable depending on the stage of the company. The firm has the ability to invest globally with typical allocations made to companies in North America. The firm is actively seeking new investment opportunities.
Michael Bianco
General Partner 

Life Science Nation

Life Science Nation (LSN) is the premier sourcing platform for market intelligence and prospect pipeline development in the life science arena. LSN enables life science professionals to generate a list of qualified global targets that are a fit for their company’s products, services, and fundraising efforts. The ability to generate these Global Target Lists (GTLs) makes life science professionals more effective and efficient. 

Biotech Phase of Development
Medtech Phase of Development
Unique Capabilities

Life Science Investor Profiles, LSN has sourced validated and maintains the largest global database of investor profiles. LSN defined 10 categories of Life Science Investor;

·         Private Equity

·         Venture capital

·         Family Offices

·         Corporate VC

·         Angel Groups

·         Large Pharma/ Biotech

·         Alternative Institutional Investors: Pensions, Endowments

·         Endowments/Foundations

·         Hedge Funds

·         Government Grants

Marketing Services, LSN consults on branding, messaging, and outbound marketing strategies. This includes developing a tagline, elevator pitch, executive summary, corporate power point presentation, and new or updated website design to fit your brand and message. LSN will develop a Global Target List of prequalified candidates to target for marketing initiatives.

Alejandro Zamorano
Tom Crosby
David Mejia
Gwen Lamar
Danielle Silva
Jack Fuller
Marlo Galvez
Laura Chess
Dennis Ford
BIO

Dennis is the founder and CEO of Life Science Nation (LSN) and creator of the Redefining Early Stage Investment (RESI) conference series. Most recently, he launched a broker-dealer entity called Boston Innovation Capital (BIC).

Dennis’s expertise is in creating and facilitating interactive dialogue between buyers and sellers. He is a big proponent of using profiling and matching technology to find that all-important business fit in the marketing and selling process. LSN provides a Match.com-like platform of product and services for scientist/entrepreneurs and early stage investors to connect with each other.

Dennis is the author of The Peddler’s Prerogative, The Fund Manager’s Marketing Manifesto, and most recently, The Life Science Executive’s Fundraising Manifesto. Dennis is an expert in sales, marketing, and business development. Dennis has distinct value in understanding the world of global alternative life science investors and how that relates to financing early stage technologies.

Life Sciences Alternative Funding United States

Life Sciences Alternative Funding (LSAF) founded in 213 is a direct investment firm based in White Plains New York. The firm focuses exclusively on providing debt capital for commercial-stage medical technology companies. The firm can allocate between USD 1M-5M per investment. The firm looks to provide flexible ?tailor-made? financing solution to companies. The firm can invest globally and is currently seeking new investment opportunities.

Steve DeNelsky
President 

Lilly Asia Ventures China

Lilly Asia Ventures is the venture capital arm of Eli Lilly that focuses on investments in the life sciences in Asia, particularly China. The firm was established in 2008 and is based in Shanghai, China. The firm is stage agnostic; investing in early, growth, and up to pre-IPO opportunities. The firm’s investment size is USD 5-20 million per company. The firm primarily invests in companies in China, but is open to companies across Asia-Pacific as long as there is some sort of China angle. The firm is actively seeking new investment opportunities.

Lilly Asia Ventures primarily focuses on therapeutics but is also interested in medical devices, diagnostics, animal health, and biotech other. The firm is most interested in products that will have a significant impact on medical care in China. For therapeutics, the firm seeks best-in-class or first-in-class products. The firm is opportunistic to the indication and the phase of development and will consider products in pre-clinical up to NDA. Historically, the firm invests in therapeutics for oncology, inflammatory diseases, and metabolic disorders.

Biotech Phase of Development
Medtech Phase of Development
Capital Structure Preference
Investment Stage Preference
Judith Li
Principal 
Michael Zhang
Investment Manager