PBM Capital Group

PBM Capital is a hybrid family office and operating company based in Charlottesville Virginia with an additional office in New York City. The firm is funded and led by the successful life science entrepreneur Paul Manning who started and sold several companies in his career. The firm can make investments ranging from approximately $5 to $1 million into companies and due to its funding structure has no requirements for holding period or capital structure. The firm makes investments in the forms of equity controlling interest in-licensing MBO/LBO growth capital and is also willing to co-invest. The firm is looking for companies located around the globe and makes around 5-15 investments in a given year.
Jayson Rieger
SVP of Business Development & Portfolio Management 

River Cities Capital Funds United States

River Cities Capital Fund is a private equity firm founded in 1994 and based in Cincinnati, Ohio. The firm manages approximately $500 million under management and is currently investing out of its 2014 vintage $200 fund. The firm looks to make investments of $5-$15 million initially up to $20 million over the investments lifetime. The firm is willing to invest throughout the United States and is looking to make approximately 4-6 equity investments over the next 6 to 9 months.

Rik Vandevenne
Director 

Safeguard Scientifics

Safeguard Scientifics is a publicly traded capital deployment firm founded in 1953 and is based in Wayne PA. The firm makes deployments from an evergreen fund and is actively seeking new investments in the healthcare sector. Initial equity placements are typically of $5-1m with the potential for a total allocation of $2-25m over the life of an investment. The firm focuses on North America with a concentration in the Mid-Atlantic and San Francisco Bay Area regions. Deployments are made at a range of stages from early-stage to growth expansion and recapitalization. Safeguard Scientifics prefers to be a sizable minority investor.
Gary Kurtzman
Managing Director 

Twin Cities Angels Fund II, LLC United States

Twin Cities Angels is an angel group that was founded in 2006 that is based in Minnesota. The group has raised two funds that are The Twin Cities Angels Fund I and II. The second fund is currently looking to invest in emerging companies. The group typically provides seed and venture capital ranging from $ 25.000 to $2 million to life science companies. The group plans to invest in 4 to 6 companies per year. Twin Cities Angels seeks to invest in companies based in the Twin Cities Area of Minneapolis/St. Paul, the state of Minnesota and within a reasonable distance, such as Western Wisconsin, Northern Iowa, and Eastern Dakotas.

Year Founded
2006
Investor Type
Biotech Phase of Development
Medtech Phase of Development
Capital Structure Preference
Investment Stage Preference
John Alexander
Chairman & Founder 

Zcube | Research Venture

Z-Cube invests strategically in technologies that benefit Zambon’s pharmaceuticals and API chemical businesses. 

Within the therapeutics sector, Z-Cube is interested in new technological platforms that enable Zambon’s therapeutic innovation (Z-Cube does not make developmental-stage investments in new chemical entities, and as Zambon only markets small molecule therapeutics, technologies related to biologics are not of interest). This includes drug delivery innovations, and other enabling technologies for therapeutics that do not have to undergo the full therapeutic approval process in order to reach the marketplace. 

Z-Cube is also interested in diagnostics, particularly point of care diagnostics, companion diagnostics and other diagnostics that are used alongside a therapeutic intervention, and diagnostics that can be used in preventative care or to lower overall healthcare costs. Zambon is also interested in diagnostic technologies used to monitor a chronic condition. 

Zambon’s therapeutic focus areas are respiratory diseases and pain (particularly chronic pain), and the firm is also interested in CNS disorders and women’s health (encompassing osteoporosis and rheumatoid arthritis in addition to ob/gyn). However in the diagnostics sector, Zambon is interested in all indications. 

Zambon is additionally interested in digital technologies that enhance communication in the healthcare space, particularly between doctor and patient or between general practitioners and specialists. This includes EMR and telehealth technologies, and devices that transmit information wirelessly. 

Zambon is also interested in innovations in high-tech chemistry, including purification of APIs, advanced crystallography, and novel custom synthesis.

Andrea Mills
Lorenzo Pradella