CVRx, Inc.

Nadim Yared
President and Chief Executive Officer 

Cydan

Cydan is an orphan drug accelerator that was founded in 213 and is based in Cambridge MA. The firm has raised $26 million dollar to derisk therapeutic assets targeting orphan indications (excluding oncology). The firm looks to option/in-license assets and form subsidiary companies around them. Cydan then derisks the assets conducting all the necessary IND enabling activities. Cydan?s investment syndicate including NEA Pfizer Ventures Lundbeck Venturefonds Bay City Alexandria then has the option to fund the NEWCo Series A round to human proof of principle Cydan is also performing due diligence on companies that are interested in receiving investment from the company's syndicate. Cydan is currently considering pre-clinical and clinical assets worldwide.
Chris Adams
CEO 

Cynvenio Biosystems, Inc. United States

Cynvenio has developed a new LiquidBiopsy technology to sequence the DNA of tumor cells isolated from peripheral blood. Key applications include longitudinal patient monitoring throughout the cancer care cycle, the detection of resistance mutations, and providing physicians with accurate molecular evidence to select the best targeted therapy for a given patient.

Cynvenio's technology can be accessed as a CLIA lab service, or  can be installed and operated inside hospital labs and cancer research centers. Cynvenio's lab has been CLIA certified since 2013 and LiquidBiopsy system deployments began in the second half of 2014.

Website:
www.cynvenio.com
Year Founded
2008
Biotech Subsector
Medtech Subsector
Biotech Phase of Development
Technology Overview
Sequencing tumor cells from whole blood
Alliance & Collaborations
Yes, US and International
Supporting Metrics or Evidence
CLIA/CAP accreditation, validations completed, generating revenue
Current Financing Needs
$15M
Current Timeline
Series C raise to scale commercial
Current Investors
Privately funded
IP Status
Core IP has issued
Recent Milestones
4 US deployments, 2 strategics
Management Team Highlights
Amgen, Nortel, Harvard, UCLA, McKinsey
Mr André de Fusco
LinkedIn logo CEO 
Maureen Cullum
CFO 

DavosPharma United States

DavosPharma’s corporate offering covers all the activities required to get a drug from conception to commercialization. DavosPharma has been filling this need since 1972, serving the pharmaceutical and life science market by providing discovery chemistry & biology, pre-clinical development, and all required CMC activities including custom synthesis of organic molecules, custom dosage formulation, and custom manufacturing of cGMP intermediates, APIs, and drug product. 

Gifford Marzoni
Vice-President Global Pharmaceutical Development 
Mike Shore
Director, Global Supply Chain & Technical Operations 

Dectiva

Website:
www.dectiva.com
Haochau Tran
Life Science Practice Leader 

Deep Knowledge Ventures Hong Kong SAR China

We are a Hong Kong-based venture fund management company focusing on mid- to long-term advanced technology investments at early stage. Through our partnership with the top analytical companies utilizing machine learning and large panel of experts, we can construct complex decision trees showing risk and return at every stage of company evolution. We routinely invest in both private and public companies specializing in biotechnology, drug discovery, personalized medicine, Big Data analysis, industrial expert systems and artificial intelligence. 

Mr Charles Groome
Mr Charles Groome
LinkedIn logo Venture Partner 
Mr Dmitry Kaminskiy
Mr Dmitry Kaminskiy
LinkedIn logo Senior Partner 

Delivering Scientific Innovation for Autism LLC United States

DELSIA is a "venture philanthropy" investment affilate of the research and advocacy foundation Autism Speaks. Our purpose is to transform lives by catalyzing the development and availability of innovative products.

DELSIA is a non-dilutive funding vehicle with the goal of improving outcomes for individuals with autism spectrum disorder (ASD). DELSIA aims to do this by enabling the translation of scientific breakthroughs and technological advances into products that improve health and quality of life for individuals with ASD and their families. 

Who and what do we invest in? DELSIA partners with for-profit companies to fund development activities necessary for delivering products that address the diverse unmet medical, behavioral health and quality of life needs of the autism community.

DELSIA accepts funding proposals from for-profit entities that include, but are not limited to:

• Entrepreneurs, start-up and small companies

• Life sciences, biotechnology and pharmaceutical companies

• Software, computer and electronic technology companies

Dr Daniel Smith
Dr Daniel Smith
LinkedIn logo President 

DeNa

Mikihiro Yasuda
Partner, Strategic Investment 

Dermspectra LLC United States

DermSpectra has developed an innovative high resolution full body imaging system designed to aid early detection of skin cancers and diseases, and revolutionize medical documentation.  The DermSpectra Automated Total Body Digital Skin Imaging (DSI) System fills a key technology gap in medical imaging, empowers physicians with an objective tool to accurately and efficiently detect and monitor skin and body changes over time and raises the bar for patient care.

Main Sector
Medtech Phase of Development
Technology Overview

The DermSpectra Total Body Digital Skin Imaging System is a proprietary solution that delivers patented high-resolution imaging, secure storage, and immediate viewing capabilities. With the most advanced level of precision in the market, DermSpectra sets the industry standard (definition, timing, lighting, image quality, data formats, secure storage, and interfaces) in digital skin imaging for dermatologists, plastic surgeons, cancer centers, clinical trials, general practitioners, and telemedicine services. The DermSpectra Total Body Digital Skin Imaging System solution strives to improve early detection of melanomas, skin cancers and treatment outcomes for patients and physicians by providing skin images that enable a comprehensive view and comparison of skin lesions and body changes over time.

Karleen Seybold
CEO 
Jarrod Winters
Chief Operating Officer 

Deton Corp. United States

Deton is developing a novel non-invasive simple-to-use sample collection device for tuberculosis (TB) patients who are unable to provide a sample.

Proper diagnosis is essential to effectively treat the more than 9million new cases of TB every year. Typically, a sputum sample is collected to run the diagnostic test. However, in 22% of adults and in all children patients, sputum is impossible to collect. These patients have to rely on inadequate alternative collection methods that are invasive, high-cost, and resource-intensive. With our device, patients can now provide a sample even in low-resource setting and find out their TB status. Deton will enable 26M samples to be tested every year.

After promising clinical data, Deton is now raising $1.6M to build an ISO 13485 disposable product and to obtain pivotal clinical validation. Discussions with multiple potential diagnostic partners and first feedback from experts at World Health Organization show significant interest in adopting the device once effective validation has been completed. 

Year Founded
2011
Main Sector
Medtech Phase of Development
Technology Overview
Cough collection to diagnose respiratory infections
Alliance & Collaborations
Confidential
Supporting Metrics or Evidence
human clinical data supporting the diagnostic
Current Financing Needs
Deton is raising a $1.6 million seed round to support 15 months of operations.
Current Timeline
Milestones: (1) develop an ISO-13485 final design disposable device (t+10 months) and (2) obtain pivotal clinical data in 50 patients (t+15 months). Deton’s third major milestone during the seed stage is to obtain Series A financing.
Current Investors
non-dilutive government grants
IP Status
The Cough Collector is protected by 2 Patent Cooperation Treaty applications fully owned by Deton: PCT/US2011/042854 –“System for airborne bacterial sample collection and analysis” and PCT/US2014/024682 – “System for breath sample collection and analysis.”
Recent Milestones
With non-dilutive funding from government grants, the Cough Collector has been tested in a study on a limited number of patients at a high prevalence site with very encouraging results.
Management Team Highlights
Deton’s team brings together more than 20 years of experience in each of engineering, medicine, and commercial operations. Our team has successfully taken a product from idea to human clinical data. Founders: Patrick Sislian, (CEO, PhD Chemical Engineering UCLA, Member of UCLA VC Fund), Stephen Chapman (VP of R&D, PhD Chemical Engineering Caltech), and Ramzi Nasr (VP of Clinical, PhD Bioinformatics UCI). Part-time: Nico Arnold (previous EVP of commercial ops at Cepheid, previous SVP at Siemens), Dr. Antonio Catanzaro (clinical expert on TB, Professor of Medicine at UCSD), and Katrina Fiedler (previous Director of Regulatory affairs at Alere).
Dr Patrick Sislian
LinkedIn logo CEO 
BIO

Patrick Sislian is co-founder and CEO of Deton. He has successful track record in product development. He has secured more than $1.2M in government grants from the NSF, NIH, DoD. He holds a Ph.D. in chemical engineering from UCLA. He serves on the Life Science Investment Committee of the UCLA Venture Capital Fund.

Nico Arnold
LinkedIn logo Business Development 
BIO

Nico Arnold, an IVD industry executive, is responsible for the commercial strategy. Nico was previous EVP of Commercial Operations at Cepheid and previous SVP at Siemens. Nico will be employed part-time and will be responsible in establishing and maintaining distribution relationships for successful product launch.