Immusoft Corporation United States

Immusoft’s mission is to develop a breakthrough platform for delivering targeted medicines — programming a patient’s own cells to become miniature drug factories.

Our technology instructs a patient's cells to constantly secrete gene-encoded medicines (biologics). It will enable new treatments by solving current delivery limitations and production challenges. We are initially targeting orphaned diseases. 

Immusoft’s platform can program cells to continually produce and secrete therapeutic proteins and rare antibodies that have been impossible to elicit with a vaccine. This approach makes possible treatments that are otherwise impractical due to short halflife, injection site reactions, production challenges or a small market size. It offers many of the benefits of traditional approaches and modern gene therapies with less risk and greater control.

Immusoft has received grants from the National Institutes of Health and Peter Thiel's Breakout Labs as well as support from private investors, including the former head of preclinical development at Seattle Genetics. We have an exclusive license option on our core technology from Caltech and have filed two additional patents covering our extensive modifications to the technology.

ISP technology could replace a lifetime of infusions with a patient’s own drug-producing cells.

Website:
www.immusoft.com
Year Founded
2009
Biotech Phase of Development
Technology Overview
Turning patients' cells into drug factories
Alliance & Collaborations
Fred Hutchinson Cancer Research Center, Discovery Genomics, Inc, University of Minnesota, The Ragon Institute, University of California San Francisco
Supporting Metrics or Evidence
Late-stage preclinical
Current Financing Needs
$3 to >$20M
Current Timeline
Preparing IND for clinical trial
Current Investors
Breakout Labs, Founders Fund Science, several angels
IP Status
multiple patents filed worldwide
Recent Milestones
GMP scale-up in preparation for clinical trial; engaging the FDA for Investigator-initiated IND; use of Sleeping Beauty Transposon non-viral vector
Management Team Highlights
Matthew Scholz (Founder and CEO) – Seasoned startup executive; founded and exited Point B Telematics. Eric Herbig, Ph.D., M.B.A. (CSO) – 15+ years of research experience and significant commercialization and management expertise. Zach Hall (Dir. of Operations) – Co-founder and operations director at two previous biomedical startups. Mei Xu, Ph.D. (Dir. of Research) – Molecular biologist with extensive research experience.
J. Zach Hall
Director of Operations 
Matthew Scholz
CEO 

InterWest Partners

InterWest Partners founded in 1979 is a venture capital firm based in Menlo Park California. The firm?s primary focus is providing venture capital to early-stage healthcare and information technology companies. The firm has raised 1 funds to date with over $2.8 billion in committed capital. The firm?s tenth fund closed in 29 at $65 million. The firm generally invests in the Series A and B rounds, initially allocating $8-12 million and up to $2 million over the life of the investment. The firm primarily invests in US-based companies but will also selectively consider opportunities abroad. The firm is actively seeking new investment opportunities.
Doug Fisher
Partner 

Joslin Diabetes Center United States

Joslin Diabetes Center is a foundation based in Boston, Massachusetts that was founded in 1898, and is the world's largest diabetes and clinical care organization.

Nandan Padukone
Vice President, Office of Commercialization & Ventures 

Life Science Angels

Life Science Angels Inc was founded in 2004 and is based in Sunnyvale CA. The group makes early-stage equity investments in a wide range of life science companies. Life Science Angels invests primarily in California but is open to investing out of state provided a round is being syndicated with a local angel group. Life Science Angels does not rule out investing outside the USA but has yet to do so. The group invests as individuals and allocation sizes are therefore highly varied but are usually of about $2-$6, Life Science Angels usually invests in rounds seeking $3 million or less. The group is interested in syndicating rounds with other angel groups.

Investor Type
Biotech Phase of Development
Medtech Phase of Development
Capital Structure Preference
Investment Stage Preference
Dr Faz Bashi
Chair Digital Health & Sciences 
Karl Handelsman
Founder & Chairman 
Allan May
Founder 

Life Science Equity Partners

Life Science Equity Partners is a private equity firm based in Palo Alto California. The firm is solely focused on life science investments. The firm will invest in companies at all stages including early-stage companies with products still in development and late-stage companies with revenue. The firm typically makes early stage investments with a 1 year exit strategy in mind. The investment size is highly variable depending on the stage of the company. The firm has the ability to invest globally with typical allocations made to companies in North America. The firm is actively seeking new investment opportunities.
Michael Bianco
General Partner 

Life Science Nation

Life Science Nation (LSN) is the premier sourcing platform for market intelligence and prospect pipeline development in the life science arena. LSN enables life science professionals to generate a list of qualified global targets that are a fit for their company’s products, services, and fundraising efforts. The ability to generate these Global Target Lists (GTLs) makes life science professionals more effective and efficient. 

Biotech Phase of Development
Medtech Phase of Development
Unique Capabilities

Life Science Investor Profiles, LSN has sourced validated and maintains the largest global database of investor profiles. LSN defined 10 categories of Life Science Investor;

·         Private Equity

·         Venture capital

·         Family Offices

·         Corporate VC

·         Angel Groups

·         Large Pharma/ Biotech

·         Alternative Institutional Investors: Pensions, Endowments

·         Endowments/Foundations

·         Hedge Funds

·         Government Grants

Marketing Services, LSN consults on branding, messaging, and outbound marketing strategies. This includes developing a tagline, elevator pitch, executive summary, corporate power point presentation, and new or updated website design to fit your brand and message. LSN will develop a Global Target List of prequalified candidates to target for marketing initiatives.

Alejandro Zamorano
Tom Crosby
David Mejia
Gwen Lamar
Danielle Silva
Jack Fuller
Marlo Galvez
Laura Chess
Dennis Ford
BIO

Dennis is the founder and CEO of Life Science Nation (LSN) and creator of the Redefining Early Stage Investment (RESI) conference series. Most recently, he launched a broker-dealer entity called Boston Innovation Capital (BIC).

Dennis’s expertise is in creating and facilitating interactive dialogue between buyers and sellers. He is a big proponent of using profiling and matching technology to find that all-important business fit in the marketing and selling process. LSN provides a Match.com-like platform of product and services for scientist/entrepreneurs and early stage investors to connect with each other.

Dennis is the author of The Peddler’s Prerogative, The Fund Manager’s Marketing Manifesto, and most recently, The Life Science Executive’s Fundraising Manifesto. Dennis is an expert in sales, marketing, and business development. Dennis has distinct value in understanding the world of global alternative life science investors and how that relates to financing early stage technologies.

Lilly Asia Ventures China

Lilly Asia Ventures is the venture capital arm of Eli Lilly that focuses on investments in the life sciences in Asia, particularly China. The firm was established in 2008 and is based in Shanghai, China. The firm is stage agnostic; investing in early, growth, and up to pre-IPO opportunities. The firm’s investment size is USD 5-20 million per company. The firm primarily invests in companies in China, but is open to companies across Asia-Pacific as long as there is some sort of China angle. The firm is actively seeking new investment opportunities.

Lilly Asia Ventures primarily focuses on therapeutics but is also interested in medical devices, diagnostics, animal health, and biotech other. The firm is most interested in products that will have a significant impact on medical care in China. For therapeutics, the firm seeks best-in-class or first-in-class products. The firm is opportunistic to the indication and the phase of development and will consider products in pre-clinical up to NDA. Historically, the firm invests in therapeutics for oncology, inflammatory diseases, and metabolic disorders.

Biotech Phase of Development
Medtech Phase of Development
Capital Structure Preference
Investment Stage Preference
Judith Li
Principal 
Michael Zhang
Investment Manager 

Lipella Pharmaceuticals Inc. United States

Development-stage pharmaceutical company with a platform technology to deliver novel therapeutics to the urinary bladder lumen for the treatment of inflammatory bladder conditions such as overactive bladder and interstitial cystitis. Our portfolio includes prodcuts in pase-I and phase-II clinical trials in the United States and overseas, as well as pre-clinical programs. We also have one program designated as orphan. In addition to therapeutics, Lipella also develops diagnostic agents to be used in connection with medical imaging.

Website:
www.lipella.com
Year Founded
2005
Biotech Subsector
Biotech Phase of Development
Medtech Phase of Development
Technology Overview
Platform technology for the local delivery of novel therapeutics to the urinary bladder
Alliance & Collaborations
Multiple
Current Financing Needs
Can be discussed
Current Investors
Private, non-institutional
IP Status
Multiple US patents, and US and international patent applications
Recent Milestones
LP-09 clinical trial completed 2013, LP-08 IND approved 2014
Management Team Highlights
Small, focused team
Jonathan Kaufman
CEO 

Longevity Biotech United States

Longevity Biotech is a privately held preclinical biotechnology company developing a new class of linear, stabilized, peptide therapeutics called Hybridtides®. 

Our objective for this meeting is to initiate fundraising (Series A) and partnership discussions to progress our preclinical neuroinflammation program into the clinic.  

To date, Longevity Biotech has demonstrated in vivo neuroprotection in a Parkinson's Disease animal model and established preliminary immunological-based biomarker end-point links to on-going clinical trials.     Longevity Biotech is encouraged to continue the development of this differentiated and potentially disease modifying therapeutic candidate to address the unmet needs across a variety of neurological disorders.  

More generally, Longevity Biotech is committed to the development of our current preclinical portfolio as well as expanding the platform breadth via licensing opportunities.  Currently, Longevity Biotech is developing GPCR based Hybridtides® for the treatment of metabolic, cardiovascular, neuroscience and oncology diseases.   In addition, preliminary data (in vitro &  in vivo) suggest the possibility of oral delivery of Hybridtide based therapeutics.

Biotech Subsector
Biotech Phase of Development
Technology Overview
Synthetic Peptide Scaffold that confers unique stability and biological activities
Alliance & Collaborations
University of Nebraska Medical Center,
Supporting Metrics or Evidence
Most recent paper: http://www.nature.com/nbt/journal/v32/n7/full/nbt.2920.html
Current Financing Needs
Series A - $15m
Current Timeline
approximately 18-24 months from clinical trials
Current Investors
Breakout Labs, NetScientific
IP Status
Several patents approved along with several still pending worldwide
Dr Scott Shandler
Dr Scott Shandler
LinkedIn logo CEO 

Longitude Capital United States

Longitude Capital is a private equity group founded in 2006 with offices in Menlo Park, California and Greenwich, Connecticut. The firm has $700 million in assets and has raised two funds, with the most recent fund closing at $385m in 2012. Longitude makes both venture-stage and growth-stage equity investments, which are typically in the $10-30 million range. Longitude Capital primarily invests in North America and the European Union but may also consider opportunities in the Middle East.

Year Founded
2006
Investor Type
Biotech Phase of Development
Medtech Phase of Development
Capital Structure Preference
Investment Stage Preference
Mark Chin