Broadview Ventures

Broadview Ventures is a Philanthropy Venture firm that was established by the Leducq Family Trust in 28 and dedicated to accelerating the translation of new and innovative programs in the CV and stroke areas. The firm is based out of Boston MA but is geographically agnostic in its investing. The firm makes equity and convertible note investments of approximately $1 million into companies that are targeting cardiovascular and neurovascular diseases. The firm invests in privately held companies at both the seed and venture stage and is currently invests in 4-5 companies per year. The firm operates under an evergreen structure and is constantly seeking new investment opportunities. While the firm will consider investments around the globe Broadview is keen to add companies based in Europe to its portfolio. Broadview has previously invested in the US Europe and Israel.
Maria Berkman
Director 
Rick Jones
Director 
Christopher de Souza
Director 

Cavidi United States

Cavidi is a Swedish based diagnostic company that has developed a novel method for measuring HIV viral load in patients recieving anti-retroviral therapy for treatment of HIV. Viral load is a critical indicator of the effectiveness of HIV therapy, and has been the standard of care in the developed world for many years. Just recently the World Health Organization (WHO) updated its recommendations to include viral load for patients in the developing world where the vast majority of HIV patients exists, and a large influx of international funding has significantly increased aceess to HIV drugs. The Cavidi method is novel in that it measures the viral enzyme reverse transcriptase (RT), and not viral nucleic acid (RNA) by polymerase chain reaction (PCR). The Cavidi method is not subject to the logistical challenges of PCR such as contamination risk. The Cavidi RT assay is much less expensive and can be performed in labs that lack the sophisitication to perform technologies such as PCR. Therfore, the Cavidi assay significantly improves access to this vitally important technology. For the past several years a manual version of the Cavidi technology has been utilized in laboratories in the developing world. The performance of the assay has been validated vs the industry leading PCR methods in many peer review publications. The company is now seeking funding to develop an automated version of the assay that will make it more widely adaptable to many laborartories. 

Website:
www.cavidi.com
Year Founded
2007
Biotech Subsector
Medtech Subsector
Biotech Phase of Development
Technology Overview
Cavidi's novel IVD technology uses Reverse Transcriptase(RT) as a marker for measuring replication competent HIV in blood (HIV viral load). Measuring viral load in HIV patients receiving anti viral therapy is now a global World Health Organization recommendation. Unlike PCR tests, Cavidi's RT assay requires minimal resources & lab footprint, can measure all subtypes of HIV, and at half the cost or less of PCR tests. The technology has been proven in over 400,000 tests in 50 markets worldwide.
Alliance & Collaborations
• Johns Hopkins School of Medicine, Uganda • Burnet Institute, Australia • University of Maryland School of Medicine IHV (Institute of Human Virology) • Karolinska Hospital, Sweden • SIDA (Swedish International Development Cooperation Agency) • Royal Free Hospital, London, UK • Harvard AIDS Institute Partnership, Botswana- • New York University School of Medicine, Kenya • Swedish Institute for Infectious Disease Control, Sweden • Virus Reference Depart
Supporting Metrics or Evidence
The Cavidi ExaVIr Load assay has been widely cited in peer review publications, and favorably compared to industry standard PCR technology. In addition to routine HIV viral load measurement, the Cavidi RT assay has demonstrated favorable performance vs. industry standard PCR for early infant HIV diagnostic (EID) market. ExaVir™ assay showed excellent concordance with real-time molecular assays Abbott M2000sp and Roche Cobas TaqMan...Journal of Clinical Microbiology 47(10): 3266-3270
Current Financing Needs
Development project completion 2015 $7M + 2016 $3M =$10M Global product launch 2016 $3M + 2017 $2M=$5M
Current Timeline
Next generation of fully automated HIV viral load test development project started in 2102. Prototype 1 and 2 now working. OEM selected Q12015, validation and verification of final design Q22015, Distribution Partner selection by Q22015, pre-series Q42015, serial production start Q12016, and CE Registration Q22016. Cash flow positive 2017.
Current Investors
Two private US investors hold majority interest
IP Status
IP is strong and broad covering key aspects of the technology methods with over 100 international patents in five patent families.
Recent Milestones
• Awarded SWECARE Export Award by Swedish MOH May 2013 • Supply Agreement signed with Load Zero Foundation in June 2013 • Presentation at UN Global Health Impact Forum May 2014 • TECH20 award as top 20 (2%) of 800 startups in Sweden June 2014 • UNITAID grant LOI accepted (3/12) June 2014, Full Application grant pending Dec. 2014 • POLS/One Technology evaluation meta study (2/2014) ranks Cavidi ExaVirLoad with top global diagnostic comp
Management Team Highlights
Experts in diagnostic technology development covering: Clinical Assay Chemistry, Devices, Instruments, Software, System Integration, QA & QC, Regulatory Strategy. Commercial scale up of new technologies in global markets with focus on emerging markets in Africa and Asia. Capital raising for start up and early stage companies.
Bob Barrett
Global Head, Business Development 

Chempetitive Group

Chempetitive Group is an integrated marketing communications agency focused exclusively on the life sciences. We work with biotech, medical device, pharmaceutical, chemical and tools/instrumentation companies of all sizes that around the globe. We develop winning strategies and campaigns that build brands and generate revenues. We love science. We understand science. And, we know how to effectively reach the scientific, clinical, medical and business communities that matter. 

Long live science. 

Visit us in San Diego, San Francisco, Chicago, Boston or Cambridge UK. 

Find out about us at http://www.chempetitive.com 

Erik Clausen
Erik Clausen
LinkedIn logo Managing Partner 
BIO

Erik Clausen is a managing partner at Chempetitive Group (http://www.chempetitive.com), a marketing communications firm that develops and implements strategies and drives results for life science and healthcare companies. Erik brings two decades of international experience helping life science, medical technology and healthcare organizations to reach and engage the right audiences.

Chiesi Ventures

Chiesi Ventures is a Venture Capital firm formed by a partnership between the Italian Pharmaceutical company Chiesi and US based VC firm Pappas Ventures. The firm is currently looking to make seed and venture stage investments into companies ranging anywhere from $2K to $5 million initially and up to $8 million over the life of the investment. The firm is actively seeking investment opportunities throughout the United States and Europe and could make as many as 2-4 new investments over the next year.
Art Pappas
Partner 

CitareTx Investment Partners

CitareTx founded in 2008 is a venture development and investment firm based in Houston Texas. The firm provides investment and incubation services to start-up and early-stage medical device companies. The firm provides seed capital (equity) ranging from $5K to $2M with follow-on capital of up to $5M. The firm also considers investment opportunities with smaller than typically accepted venture capital market size thresholds. The firm is geographically agnostic but prefers companies to be based in Texas. The firm is actively seeking new opportunities.

Jeffery Sheldon
General Partner & Managing Director 

Correlation Ventures United States

Correlation Ventures is a venture capital firm that founded in 2010 and is based in San Diego, California with an additional office in Palo Alto, California. The firm currently has approximately $165 million in total assets under management. The firm typically makes investments ranging from $0.25 million to $5 million over the life of the company, and the first investment will be not larger than $2.5 million. The firm’s preferred capital structure is convertible preferred equity or convertible loan. Correlation Ventures will consider invest in any industry segment at any stage, but there must be at least one other venture capital firm making their first investment in the company in this round. The firm only invests in US-based companies. 

Correlation is extremely opportunistic when it comes to investments in the life sciences space; with that being said the firm's specified sectors and sub sectors of interest may or may not be an area in which Correlation Ventures is currently looking to allocate capital to. The firm has made a number of investments in companies in the life sciences space, and has mainly invested in companies in the biotech therapeutics and diagnostics space. The firm's current portfolio includes biotech therapeutics and diagnostics firms developing products targeting endocrine, metabolic, and nutritional diseases, musculoskeletal system and connective tissue, neoplasms, cancer, and oncology, genitourinary system, and infectious and parasitic diseases.

Year Founded
2010
Investor Type
Medtech Phase of Development
Capital Structure Preference
Investment Stage Preference
David Coats
Managing Director 

Cynvenio Biosystems, Inc. United States

Cynvenio has developed a new LiquidBiopsy technology to sequence the DNA of tumor cells isolated from peripheral blood. Key applications include longitudinal patient monitoring throughout the cancer care cycle, the detection of resistance mutations, and providing physicians with accurate molecular evidence to select the best targeted therapy for a given patient.

Cynvenio's technology can be accessed as a CLIA lab service, or  can be installed and operated inside hospital labs and cancer research centers. Cynvenio's lab has been CLIA certified since 2013 and LiquidBiopsy system deployments began in the second half of 2014.

Website:
www.cynvenio.com
Year Founded
2008
Biotech Subsector
Medtech Subsector
Biotech Phase of Development
Technology Overview
Sequencing tumor cells from whole blood
Alliance & Collaborations
Yes, US and International
Supporting Metrics or Evidence
CLIA/CAP accreditation, validations completed, generating revenue
Current Financing Needs
$15M
Current Timeline
Series C raise to scale commercial
Current Investors
Privately funded
IP Status
Core IP has issued
Recent Milestones
4 US deployments, 2 strategics
Management Team Highlights
Amgen, Nortel, Harvard, UCLA, McKinsey
Mr André de Fusco
LinkedIn logo CEO 
Maureen Cullum
CFO 

Deep Knowledge Ventures Hong Kong SAR China

We are a Hong Kong-based venture fund management company focusing on mid- to long-term advanced technology investments at early stage. Through our partnership with the top analytical companies utilizing machine learning and large panel of experts, we can construct complex decision trees showing risk and return at every stage of company evolution. We routinely invest in both private and public companies specializing in biotechnology, drug discovery, personalized medicine, Big Data analysis, industrial expert systems and artificial intelligence. 

Mr Charles Groome
Mr Charles Groome
LinkedIn logo Venture Partner 
Mr Dmitry Kaminskiy
Mr Dmitry Kaminskiy
LinkedIn logo Senior Partner 

Delivering Scientific Innovation for Autism LLC United States

DELSIA is a "venture philanthropy" investment affilate of the research and advocacy foundation Autism Speaks. Our purpose is to transform lives by catalyzing the development and availability of innovative products.

DELSIA is a non-dilutive funding vehicle with the goal of improving outcomes for individuals with autism spectrum disorder (ASD). DELSIA aims to do this by enabling the translation of scientific breakthroughs and technological advances into products that improve health and quality of life for individuals with ASD and their families. 

Who and what do we invest in? DELSIA partners with for-profit companies to fund development activities necessary for delivering products that address the diverse unmet medical, behavioral health and quality of life needs of the autism community.

DELSIA accepts funding proposals from for-profit entities that include, but are not limited to:

• Entrepreneurs, start-up and small companies

• Life sciences, biotechnology and pharmaceutical companies

• Software, computer and electronic technology companies

Dr Daniel Smith
Dr Daniel Smith
LinkedIn logo President