Excel Venture Management United States

Excel Venture Management is a venture capital firm that was founded in 2008 and is based in Boston, Massachusetts. The firm has managed one fund with committed capital of $125 million, and the firm is currently raising the second fund. Excel Venture Management seeks to make equity investments into life science companies from early to late stages. The typical investment size ranges from $3 million to $ 5million. The firm plans to invest in 4-5 companies over the next 6-9 months and prefers to invest in companies based in US.

Year Founded
2008
Investor Type
Medtech Phase of Development
Capital Structure Preference
Investment Stage Preference
Eric Zimmerman
Kevin Liang

Flagship Ventures

Flagship Ventures is an early-stage venture capital firm founded in 2 and located in Cambridge MA. The firm has $9 million AUM. Flagship Ventures invests in therapeutics and in medical technology and makes initial allocation of typically $5-$5 million with the possibility of follow-on investments for a total commitment of up to $7 million-$15 million.
David Berry
Partner 

Fusion Genomics Corporation Canada

Fusion Genomics Corp (FG) is a molecular diagnostic test  development company that is introducing diagnostic kits with companion analysis software that offer superior clinical information, faster turn-around-times and ease of use for hospitals and clinical laboratories. Fusion is the first of two companies in the world to bring a validated Next Generation Sequencing (NGS) diagnostic test complete with highly secure cloud based analytical service for childhood cancers (ChildSeq-RNA SRCT) into the clinic. This test was validated in the renowned medical testing facility at the Texas Children Hospital, Baylor College of Medicine.

FG is completing development of kits for facilitating absolute diagnosis of pediatric and adult blood cancers. In addition, FG has partnered with the Royal Tropical Institute (Dutch: Koninklijk Instituut voor de Tropen; KIT) a World Health Organization reference diagnostic laboratory for infectious diseases to design the next generation of assays for the detection of infectious diseases including drug-resistant forms of tuberculosis, influenza, hepatitis and hemorrhagic fevers including Ebola.

Year Founded
2013
Biotech Subsector
Medtech Subsector
Biotech Phase of Development
Medtech Phase of Development
Technology Overview

Fusion Genomics Corporation (FG) develops molecular diagnostic tests that utilize next-generation sequencing (NGS) technologies. All of FG’s tests can be used with any of the widely adopted NGS instruments on the market. Data is analyzed using FGF’s secure FusionCloud, providing diagnosis –enabling DNA sequence information to the clinician.

Most NGS based diagnostic efforts can be divided into two categories: 1) whole genome sequencing (WGS), where the entire DNA of an individual (or a pathogen) is sequenced, and 2) target-capture sequencing (TCS), where only diseased portions of DNA are sequenced. TCS produces 1000 times less data than WGS. The expensive computational resources required for analysis of WGS data prevents it from being adopted for routine clinical use. Therefore, TCS is more suitable and appealing in frontline diagnostic environments.

TCS uses either PCR or “DNA baits” as the underlying technology to “capture” disease-specific regions of the genome. PCR-based methods suffer from limitations described earlier. FG uses proprietary Quantum ProbesTM, an enhanced form of DNA baits, in all its tests. Quantum ProbesTM allow for nearly limitless expansion of genetic targets and rapid development of new tests as well as patentable techniques that are beyond the capacity of PCR. The superior advantage of Quantum ProbeTM, coupled with FusionCloud analysis and reporting, will drive the successful adoption of the tests. 

Alliance & Collaborations
Texas Children Hospital, Baylor College of Medicine (Houston, USA), British Columbia Centre for Disease Control (Vancouver, Canada), Royal Tropical Institute / Koninklijk Instituut voor de Tropen (Amsterdam, Netherlands)
Supporting Metrics or Evidence

The Fusion Genomics team published a very well received peer-reviewed publication which demonstrated that their technology was more sensitive, accurate, rapid and comprehensive than current industry standards such as PCR and FISH.  This study can be found at here.

Current Financing Needs

 $0.5-1M to complete seed round

Current Investors

Founders, board members, family and friends.

IP Status

Patent applications are pending.

Management Team Highlights

Fusion Genomics Corporation’s team has established expertise in next-generation sequencing, diagnostic test and software development, and information technology.

Mohammed Qadir, PhD., Chief Executive Officer and Chief Scientific Officer has over 17 years of research experience; the last 10 were at the British Columbia Cancer Agency. As part of his early training, he worked with world-renowned experts in genomics and drug development and is the co-inventor of the ChildSeq assay and ChildDecode.

Greg Stazyk, Chief Technical Officer has over 20 years of experience in senior positions in the IT industry. Mr. Stazyk was the IT lead for one of Canada’s largest bioinformatics computing platform at the BC Cancer Agency’s Genome Sciences Centre (GSC). Mr. Stazyk was the senior manager at PMC-Sierra Inc. responsible for its global computer systems operation.

Brian Kwok, VP of Product Development has close to 10 years of experience in molecular biology and genomic technologies including leading edge next-generation sequencing. Mr. Kwok has worked in combinatorial drug screening and led the development of the ChildSeq assay.

Dr. Poul Sorensen MD, PhD: Board member and clinical expert. Dr. Sorensen is a world-renowned pediatric pathologist and is the Johal Chair in Childhood Cancer Research at the University of British Columbia, as well as a professor in the Department of Pathology and a Senior Scientist at the BC Cancer Research Agency (Vancouver, Canada). Dr. Sorensen is also the Chair of the Translational Research committee of the Children’s Oncology Group.

Mohammed Qadir
Chief Scientific Officer 

Golden Seeds

Golden Seeds is an investment group that was founded in 25 and is headquartered in New York with other offices in Boston Silicon Valley and Texas. The group currently invests out of the Golden Seeds angel network and the Golden Seeds venture funds. The group has managed 3 venture funds that are Golden Seeds Fund LP Golden Seeds Fund 2 LP and Innovate New York LP Fund. The Golden Seeds angel network has 32 members of which 1 are life science investors. Golden Seeds invests in companies with a female founder or CEO or with women in other C-level positions or with at least 1% of equity owned by women. Golden Seeds prefers to invest in companies with a valuation under $5 million, the group?s first-round equity investments generally range from $ .25 million to $2 million. The group invests in companies based across the US and Canada.
Bill Whitaker
Managing Director Co-Chair Life Science Section 

Green Park & Golf Ventures

Green Park & Golf Ventures (GPG) is a family office based in Dallas Texas. The firm was founded in 211 and is focused on healthcare companies. The firm makes seed venture and growth stage investments. The firm typically provides seed and Series A equity financing in the range of $1K to $1M per portfolio company. The firm generally acts as the lead investor and is open to invest in syndicates. The firm primarily invests in companies that are based in Texas but is open to opportunities across North America. The firm is actively seeking new investment opportunities.
Clay Heighten
Founding Partner 
JR Garcia
Principal 
Carl Soderstrom
Founding Partner 

Greenhouse Capital Partners United States

Greenhouse Capital Partner is a venture capital firm that was founded in 2006 and is based in Sausalito, California. The firm selectively makes equity investments into life science companies in seed stage and series A financing round, but it also provides growth equity to highly capital efficient companies that can achieve cash flow break-even within two years. The typical investment size ranges from $0.25 million to $2 million.The firm focuses on investments in US based companies.

Eric Desai
Principal 

H.I.G. BioVentures

H.I.G. BioVentures is the life science investment affiliate of H.I.G. Capital and has offices across the USA. H.I.G. BioVentures has assets under management of $4m and is investing from its second fund which closed at $268m in 212. The firm typically makes initial equity investments of $3-7m with the potential to invest up to $2m over the life of an investment. While most of H.I.G. BioVentures? portfolio companies are US-based the firm will consider opportunities worldwide.
Enoch Kariuki
Vice President 

Health Beacons United States

Health Beacons is an early stage medical device company that is revolutionizing the standard of care for marking and surgically removing non-palpable breast tumors. Physicians are actively seeking an alternative procedure and are enthusiastic about ours, which employs RFID markers that are read with handheld readers, because it addresses all the shortcomings of the current method.  We have a fully functional prototype that has been used successfully in almost 40 human cases and are working on our 510K submission. Investment to date has been from founders, friends and family.  We are currently seeking $1.5M in an equity round to support regulatory clearance, and will require another $2-3M for commercialization which is planned for Q1 2016.

Year Founded
2008
Main Sector
Medtech Phase of Development
Current Investors

Founders, friends and family

Nancy Confrey

Horizon Technology Finance United States

Horizon Technology Finance is a venture lending, investment and financial services management company that was founded in 2003 and is headquartered in Farmington, Ct with additional offices in Walnut Creek, CA and Reston, VA. The firm controls approximately $200 million in assets under management and look to provide senior or subordinate loans to companies in the range of $2 to $20 million dollars, and often syndicates much larger deals. The firm prefers to lead or co-lead investments that they are involved in and looks to be involved in 15 deals in the next 6-9 months. The firm provides capital to companies located throughout the United States and Canada.

Year Founded
2003
Medtech Phase of Development
Capital Structure Preference
Investment Stage Preference
Jerry Michaud

Iliad Ventures

Iliad Ventures is a private investment firm funded entirely by its partners that is based in New York City. The firm is looking to make equity investment into early and mid-stage life science companies ranging from $5 to 2 million initially. The firm looks to get involved in Seed and Series A Rounds. The firm could make as many as 6 investments over the next 12 months and looks to invest in companies located throughout the United States Europe and Israel.
Steve Tsetsekos
General Partner