Advent Life Sciences United Kingdom

Advent Life Sciences

We invest predominantly in early and mid-stage life sciences companies.  We seek to back truly innovative companies that have a first-in-class or best-in-class approach and who are looking for a well-connected partner on the road to success.

Our investments cover a range of sectors within life sciences, including new drug discovery, enabling technologies, med tech and diagnostics.Advent Life Sciences is one of Europe’s leading venture teams investing in life sciences businesses. We are a deliberately small, and highly focused team of senior individuals, with long-standing track records of entrepreneurial and investment success across the UK, Europe and the USA.

Real people. Real insight. Real value.

Innovation. Clarity. Execution.

 

 


Dr Dale Pfost
Dr Dale Pfost
LinkedIn logo General Partner 

AFH Holding & Advisory

AFH Holding & Advisory LLC is a boutique investment banking firm that offers financial advisory services. The firm focuses on alternative public offerings marketing strategy planning capital structuring and mergers and acquisitions advisory. Its clientele include Carlisi Natural Gas Inc. Fossil Energy Group LLC Kaikai Technology Co. Ltd. and Yi Xin Copper Co. Ltd. AFH Holding & Advisory LLC is based in Beverly Hills California with an additional office in Pudong China.
Amir Heshmatpour
Founder & Managing Director 

Aisling Capital

Aisling Capital is a private equity group based in New York with over $1.6 billion in assets under management. Aisling is currently looking for new firms for potential investments for the firm?s third fund. The firm looks to make investments in companies seeking to raise a total round of $2-5 million. The firm looks to invest in companies globally with a focus on companies located in the United States.
Dennis Purcell
Founder and Senior Advisor 

ALIAD France

ALIAD is the venture capital subsidiary of the Air Liquide Group (L'Air Liquide S.A.), one of the largest multinational providers of industrial and medical gases and related activities, headquartered in Paris, France. The healthcare division of the Air Liquide Group has been playing a significant role in healthcare with over €2 billion in revenue. 
ALIAD aims to promote the Group’s growth and access to innovations through taking minority stakes in innovative technology start-ups outside the Group. ALIAD can lead or co-invest with other investors. Typical allocations are made in equity and range from €1-10 million. ALIAD is currently seeking new opportunities across a wide geography, including Western Europe, North and South America and Asia.

Greg Fleming
Investment Director 

Allurion Technologies United States

Allurion Technologies was founded in 2009 to develop an intragastric balloon for weight loss that can be administered without surgery, endoscopy, or anesthesia. Obesity is a worldwide epidemic, yet only 2% of patients who qualify for bariatric surgery go on to be treated. Several endoscopic weight loss techniques are under development for the overweight and obese population, but they are restricted to the gastroenterologist call point and more expensive due to the costs associated with endoscopy and anesthesia.

Allurion's Elipse intragastric balloon is swallowed and excreted and can be delivered without endoscopy or anesthesia, thereby making it accessible to non-endoscopists and to consumers at a lower price point.

Allurion is currently a clinical-stage company seeking funds for further clinical work and OUS commercialization.

Year Founded
2009
Main Sector
Medtech Subsector
Medtech Phase of Development
Technology Overview
Swallowed and excreted intragastric balloon that resides in the stomach for several months before self-emptying and passing through the GI tract.
IP Status
Three US patents allowed. 5 US patents pending. 15+ WW patents pending.
Shantanu Gaur

Altravax United States

Altravax is a privately held biopharmaceutical company focused on developing first-in-class biological products to fight infectious diseases or treat other indications. The Company has a robust pipeline of candidates at various preclinical stages of development including a therapeutic vaccine against chronic hepatitis B infection. Altravax seeks investment opportunities to develop these lead candidates for clinical testing.

Website:
www.altravax.com
Year Founded
2009
Biotech Subsector
Biotech Phase of Development
Technology Overview
: Altravax’s proprietary Immunogen Optimization System™ (IOS) offers unique opportunities to create many types of novel biopharmaceutical product candidates with significantly improved safety, efficacy, manufacturability, stability, and toxicity for preclinical evaluation in a cost-effective manner.
Supporting Metrics or Evidence
A novel therapeutic hepatitis B vaccine containing improved antigen sequences has shown the abilities to induce superior antigen-specific B-cell and T-cell immune responses in animal experiments. The vaccine could potentially break immune tolerance, restore T-cell exhaustion, and have a significant therapeutic impact in chronic hepatitis B patients
Current Timeline
24-30 months to IND and 4 years to human POC with sufficient funding in place.
Current Investors
Arthur Ventures & an angel investor
IP Status
US and PCT filed.
Dr Sean Du
Co-Founder, Chief Operator Officer 

American Heart Association

The American Heart Association is a non-profit foundation that was founded 1924. The firm looks to make equity investments into companies of up to $25 generally in the seed or series A stage. The firm is looking to invest in companies located throughout the United States and is currently seeking new investment opportunities.
Website:
www.heart.org
Investor Type
Biotech Subsector
Biotech Phase of Development
Medtech Phase of Development
Capital Structure Preference
Investment Stage Preference
Ross Tonkens
Director Science and Technology Accelerator 

Amorphex Therapeutics United States

Amorphex Therapeutics is an early clinical stage company that was founded to develop products for sustained ophthalmic drug delivery using patented TODDD™ technology. Topical ophthalmic pharmaceuticals are a $5+Billion market, but inaccurate and inefficient delivery systems, poor compliance and excessive side effects undermine their clinical benefits and true sales potential. TODDD™ is a soft, non-invasive device that is completely concealed under the eyelid and continuously delivers therapeutic levels of drug 24/7 over several months. While TODDD™ is soft and flexible, unlike soft contact lenses, it doesn’t contain appreciable water and avoids the surface drying and resulting deposits that irritate and deter many contact lens wearers. In recognition of the potential benefits and their developmental progress, the company’s founders have been awarded three National Institutes of Health (NIH-SBIR) grants for the TODDD™ technology totaling $2.5 million.

TODDD™ has issued patents in major markets and has been successfully tested in safety studies, animal trials with drugs and without drug in humans.

Amorphex is seeking to fund small, 30 - 40 subject, human clinical trials of TODDD™ delivering timolol, prostaglandin and both drugs simultaneously. This funding will also support pre-clinical development of TODDD™ for ocular allergy and inflammation applications.  These milestones will drive dramatic increases in valuation and corporate partner interest.

Year Founded
2010
Main Sector
Biotech Subsector
Medtech Subsector
Biotech Phase of Development
Medtech Phase of Development
Supporting Metrics or Evidence
Successful safety studies, animal trials and human proof of concept studies.
Current Financing Needs
$1.1M to regulatory milestone, $2.1M to clinical milestone, $4.6+ M to complete plan
IP Status
Patents issued in US, Europe, Japan and Canada
Mr Robert Thompson
CEO 
Mr Charles Leahy
VP of Clinical Affairs 

Antibody Solutions United States

Antibody Solutions is a premier developer of therapeutic, diagnostic and critical reagent antibodies. Our platforms include human antibodies from transgenic OmniRats™, Hybridoma Libraries™, and high-throughput flow-cytometry screening of cell-associated targets. We provide full technical support and project management with all services performed in the USA. 

Website:
www.antibody.com
Year Founded
1995
Service Provider Type
Medtech Subsector
Biotech Phase of Development
Unique Capabilities

Human Ab producing OmniRats™ 

Hybridoma Libraries™  

High-throughput flow-cytometry screening 

Proven record of success

In Vitro Ab Production

Proven track record of success

John Kenney
President