TriNet

Robin Engstrom
Regional Sales Consultant, Life Sciences and Biotech 
Glenn Harvin
Regional Sales Consultant, Life Sciences and Biotech 
Caleb Monticalvo
Field Marketing Coordinator 
Jeff Nedved
Regional Sales Consultant, Life Sciences and Biotech 

Tutela Industries, LLC. United States

Tutela Industries is a Health IT startup developing patient-centric mHealth solutions to reduce readmissions and significantly enhance patient engagement. Tutela has developed a proprietary and breakthrough low cost, secure framework, TutelaConnect™, for hospital-based clinicians to communicate (voice, video, and data) securely to remote caregivers, both outside and inside the hospital environment. Even though a majority of hospitals have implemented electronic health records for identifiable patient data exchange within the hospital, the secure HIPAA compliant capture and exchange of unstructured patient information outside the hospital remains a challenge, impacting decision making, care coordination and informed consent.

In a recent benchmark data security report, over 90% report that their number one security risk is the unsecure exchange of patient information (phone, text. email) initiated from inside the hospital. 88% of hospitals attribute data breaches to employee negligence and the lack of mobile device security. The cost of these breaches exceeds $5.6 Billion per year, averaging $1M per year per hospital. Most hospitals are still struggling to create a unified communication strategy that meets stringent security, HIPAA compliance requirements while meeting clinical workflow and ease of use demands. Ubiquitous solutions are not cloud-based which makes the use case for patient engagement costly, complicated and difficult to scale. Ultimately, restricting the use to the few and not the many. The worldwide available market for interactive patient engagement solutions exceeds $2.3B and the initial target market, the high-risk Neonatal Intensive Care is estimated at $160 Million. The TutelaConnect™ Platform, can enter the market within current reimbursement and regulatory environments, and is ready to launch H2 2015 through sales to the first  pilot hospitals.

The competitive landscape includes large players in adjacent markets; Cisco/PolyCom for enterprise video solutions; Phillips, medical device manufacturer for remote monitoring, and electronic health record companies, Cerner and EPIC. Small niche players, Mommy’s Ear, Angels Eye and NICView offer limited pieces of a unified patient engagement communication tool.  None to date provide a cloud-based, platform agnostic, secure and HIPAA compliant method that eliminates costly licenses, expensive hardware and ongoing endpoint configuration and IT support requirements.

A strong competive position, highly differentiated use cases, a clear Freedom to Operate and patent potential, as well as, a highly experienced management team, early traction and favourable regulatory trends provide a great opportunity for success.

Website:
www.itutela.com
Year Founded
2010
Main Sector
Medtech Subsector
Indication
Biotech Phase of Development
Medtech Phase of Development
Technology Overview

In 2010, Tutela company founders observed that a great need existed in intensive care areas for clinicians to communicate with patient’s circle of care; family members, advocates and aids to streamline discharge processes, prevent readmissions and provide a better experience. After 1000+ technical, economic and user interviews, a minimally viable prototype was developed for use in high risk areas, such as the neonatal intensive care unit (NICU). Three of the more novel components of the system include a secure access distribution mechanism; role-based mechanism to authenticate all users (both inside and outside the hospital) and their relationship to a third-party(patient), a method in which the capture of all the information including users, 3rd party (patients), clinical notes, electronic health record information, and any voice, video or audio transmission is secured at rest and in transit fulfilling compliance regulations, and a method to capture, store, forward and assign all relevant data from each engagement session to a  3rd party (patient) eliminating licenses and user accounts. The TutelaConnect Platform provides the first multi-platformed, cloud-based interactive patient engagement system that securely connects remote care givers to the bedside of critically ill patients using a platform agnostic video conferencing technology.

Alliance & Collaborations
First three pilots and customers include; Johns Hopkins Hospital, University of Pennsylvania Children's Hospital, Georgetown University Hospital NICU. Discussions are underway with seed investors TEDCO(follow-on), Maryland Ventures and Gulf Ventures.
Supporting Metrics or Evidence

Strong evidentiary support that patient and family engagement plays a vital role in experience and outcomes exist including a direct correlation with patient satisfaction, discharge planning and reduced readmissions; Fairview, Cope and CMS studies. The ongoing clinical trial and the voice of customer data (1000+ technical, economic and user interviews) have shown a technical deployment in less than 15 hours at an academic medical center, an improvement in clinical efficiency in the record of unstructured communications, an increase in patient satisfaction that impacts reimbursement and a slight reduction in length of stay that saved the hospital, $13,000. Hard numbers will be available at the completion of the trial in Q1 2015. The system is considered a Class One Exempt device. The FDA requires only that the NICULink, mobile device and the TutelaConnect Platform be registered 30 days prior to commercialization.

Current Financing Needs

$800,000. Amount can be staged to support product development completion, headcount and pilot costs.

Current Timeline

6-9 months away from commercialization.

Current Investors

TEDCO($100k), Founders Capital ($300k) and Gulf Ventures(GVC)committed ($200k)

IP Status

Freedom to Operate Analysis and Provisional Patent was filed in December 2014.

Recent Milestones

To date, 90% of the first product platform has been developed. Technical and clinical workflow usability and feasability testing is complete. In December 2014, beta testing of a portable mobile device connected to the platform began in the NICU at Georgetown University Hospital. Over 500 clinician-to-family interactive video sessions have been completed with 97% "game changer" endorsement. A small reduction in length of stay, 3.9 days, equated to savings of $13,000 during a 3 week period. Additional pilots are lined up at Johns Hopkins and UPENN in the adult and pediatric service lines, which will lead to first sales A committment for $200k was received in December. A pipeline and contact with other interested hospitals including Loma Linda, Stanford, University of Tennessee has been initiated. Soft product launch is targeted for October 2015 at a national neonatal conference.  

Management Team Highlights

We have an experienced and well rounded team with 80+ years expereince in network security, medical device and software product development and clinical data support sales and marketing. Brad Pollard, CTO, has 15+ years in startup expereince. His last position prior to Cisco was with Source Fire, sold to Cisco for $2.3B. Karen Alder, CEO, has 20+ years in sales and accounting with health IT startups. Her last position was with TheraDoc, which was sold to Premier for $117M. Richard Smith, COO, 25+years experience in medical device product development. Led successful product launches at GE and Brainz. Brainz was successfuly exited in 2008. Clinical advisors are well recognized leaders in neonatology and the adult critical care space.

Karen Alder
Co-Founder/CEO 

Twin Cities Angels Fund II, LLC United States

Twin Cities Angels is an angel group that was founded in 2006 that is based in Minnesota. The group has raised two funds that are The Twin Cities Angels Fund I and II. The second fund is currently looking to invest in emerging companies. The group typically provides seed and venture capital ranging from $ 25.000 to $2 million to life science companies. The group plans to invest in 4 to 6 companies per year. Twin Cities Angels seeks to invest in companies based in the Twin Cities Area of Minneapolis/St. Paul, the state of Minnesota and within a reasonable distance, such as Western Wisconsin, Northern Iowa, and Eastern Dakotas.

Year Founded
2006
Investor Type
Biotech Phase of Development
Medtech Phase of Development
Capital Structure Preference
Investment Stage Preference
John Alexander
Chairman & Founder 

TYLT Lab

TYLT Lab was founded in 213 and has offices in Santa Monica CA and in Hong Kong. TYLT Lab invests across a variety of sectors including biotech and medical technology and will be raising a second fund in 215. TYLT Lab typically invests $5-$1 million and prefers to invest in seed or Series A rounds. The firm makes up to 12 allocations per year and is interested in opportunities globally, companies developing products that can impact healthcare delivery in emerging markets such as China or India are of particular interest.
Gerard Casale
Managing Director 

UMass Venture Development Center

Website:
www.umb.edu
Bill Brah
Executive Director 

US Angel Investors

John Ricci
Founder 

Valley Fever Solutions United States

We are focused on Valley Fever, an orphan disease that kills 150 people a year. Thousands are taking drugs for life, and many others have no effective drug therapy options. Nikkomycin-Z is a new, first in class antifungal ready for Phase II testing. Teliable animal models suggest NikZ will be effective. 

With our guidance, the NIH is funding two Phase II trials starting about late 2015. We would like to run a third, sweet-spot-of-market trial as soon as we secure funding. Our Chief Medical Officer is lead author on an NIH study on standard of care drugs for this disease. We plan to try NikZ under a simlar protocol as soon as we secure support. 

Valley Fever Solutions has made our API at pilot scale. The process is robust and repeatable. We are ready to make a large batch as soon as we secure funding. We expect the proof of concept trial can reach at least early readout within 18 months of funding. This can be achieved for less than $10M.

Year Founded
2007
Biotech Subsector
Biotech Phase of Development
Technology Overview
Nikkomycin-Z is a Nucleoside Peptide, first in class new anti fungal.
Alliance & Collaborations
Extensive NIH support
Supporting Metrics or Evidence
NikZ is fungicidal in mice, the best current drugs only limit further fungal growth (fungistatic). We have promising results in some dogs.
Current Financing Needs
$10M for Phase II proof of concept
Current Timeline
Ready to make API (8-12 months) for Phase II trials (following 8-12 months)
Current Investors
Founders
IP Status
12 years market exclusivity - OOPD, QIDP; new patents pending
Recent Milestones
RC3 grant brought our process to pilot scale API; NIH grants funded for Phase II trial, second parallel trial waiting for API (NIH sourcing)
Management Team Highlights
David Larwood (CEO) did early work on two $1B drugs, VP at two pre-Nasdaq companies (took one public, the other later reached $2B valuation); John Galgiani (CMO) is one of the most respected and well known clinicians in Valley Fever
David Larwood
David Larwood
LinkedIn logo CEO 
BIO

David Larwood has been a chemist for decades, most recently leading Valley Fever Solutions as CEO since it was founded in 2007. From 1997 to 2005 he was VP at two pre-NASDAQ companies, taking the second one public for four years until it was sold. The first later went public and reached $2B valuation.

His PhD research at UCSF supported the foundations for PEGylated liposomes, including Doxil. He was the first to make suitable PEGylated lipids and made some of the earliest of these novel liposomes.

He was the first to make Iotrolan, still produced by 12 companies decades later.

VDDI Pharmaceuticals United States

Advances in synthetic chemistry and drug screening techniques have flooded the pharmaceutical industry with potential new drugs. At the same time, industry consolidation and financial pressures on R&D budgets have reduced the ability of biotech and pharmaceutical companies to develop early stage drugs. As a result of these market forces, large pharmaceutical companies have restricted their drug development activities to "blockbuster" drugs ($1 billion revenues) with proven efficacy. Promising early-stage drugs developed in emerging biotech and pharmaceutical companies, and university research laboratories are being shelved. 
VDDI Pharmaceuticals has been formed to capitalize on these opportunities. The Company will license attractive product development opportunities from academic institutions, biotech firms and pharmaceutical companies. VDDI Pharmaceuticals will focus on pharmaceutical product opportunities where general proof-of-principle has already been established in pre-clinical or human testing, and where the products are novel and offer significant potential advantages to products currently in the market or in development. VDDI Pharmaceuticals will pursue early-stage products qualifying for fast track approval, primarily in the areas of cancer, cardiovascular disease and infectious disease and develop the products through Phase II of the required regulatory approval processes. The developed products will be licensed to existing pharmaceutical companies for product marketing, thereby generating license fees and ongoing royalties for VDDI Pharmaceuticals.

As its name suggests, VDDI Pharmaceuticals utilizes a virtual business model. Virtual drug development entails: (i) a small core group of employees responsible for strategic management, regulatory strategy, and financial control, (ii) outsourcing all non-core business functions, including preclinical and clinical drug development, and (iii) electronic data capture and data submission to regulatory authorities. By adopting this model, VDDI Pharmaceuticals believes it can reduce total drug development program costs by at least 25% and development times by up to 50%.

Year Founded
2000
Biotech Subsector
Biotech Phase of Development
Technology Overview
Rhabdomyolysis results from muscle injury that leads to the release of myoglobin, which is then deposited in the kidney; acute renal failure (ARF) results.
Alliance & Collaborations
Heyuan Co-Source, Hefei, PRC for xemilofiban only. Vanderbilt University for PIP Inhibitors
Current Financing Needs
$2.5 M
Current Timeline
Orphan Designation 1Q 2015, FIle SBIR/STTR APril 5, 2015, Pre-IND work June 2015 FIle IND July 2016, Sept, 2016 Phase I
Current Investors
$14 Million for previous assest and xemilofiban and $375 SBIR STTR NIH for PIP inhibitor program. Angels and NIH SBIR/STTR
IP Status
Patent and application serial numbers 8,367,669, 13/759,987, 61/761,182
Recent Milestones
VDDI Vanderbilt Option Agreement Signed Dec 2013
Management Team Highlights
R. Stephen Porter, Pharm. D. - Chairman, CEO and President: Dragon Bio-Consultants ,Therapeutic Antibodies, Am. Cyanamid
Stephen Porter
President, CEO 

Ventac Partners United States

Ventac Partners is a dedicated life science investment and consulting firm with offices in Europe, USA and Asia. Ventac Partners has a strong track record in founding new innovative companies, fund raising and supporting M&A transactions.

All partners are experienced and hands-on life science entrepreneurs with proven track-record in successfully starting, funding, growing and expanding international life science companies.

Neil Thomas
Neil Thomas
LinkedIn logo Partner