Wellington Partners Germany

Wellington Partners is a venture capital firm based in Munich, Germany, with an additional office in Zurich, Switzerland. The firm specializes in early-stage and growth capital investments in the Technology and Life Sciences sector. The firm has approximately €800M AUM and is currently investing out of a €100M fund for Life Science companies. Depending on the stage of the company, the firm can allocate up to €10M over the life of the investment. The firm can also lead or co-lead financing rounds of up to €30M or higher with syndicates. The firm focuses on European companies but will consider US-based companies with activities in Europe. The firm is actively seeking new investment opportunities.

Year Founded
1990
Biotech Phase of Development
Medtech Phase of Development
Capital Structure Preference
Investment Stage Preference
Rainer Strohmenger
General Partner 

Western Oncolytics, Ltd. United States

Western Oncolytics is developing a novel immunotherapy to treat a wide range of solid tumors.  Our therapy is an oncolytic vector with multiple therapeutic transgenes that both stimulate the immune system and remove local tumor immune inhibition.  The vector is engineered to avoid the immune system itself, thus overcoming a major drawback in competing designs.  It is the only therapy in the world with these leading attributes.  Western Oncolytics' therapy works in combination with other treatments, e.g. checkpoint inhibitors, and is capable of systemic (intravenous) delivery. 

Our team comprises the leading scientists, clinicians, and regulatory experts within our field, including entrepreneurs who successfully exited companies with earlier technologies.  In comparison animal testing measuring tumor growth and survival, our therapy performed far better than earlier, clinically-proven oncolytic therapies.

Western Oncolytics is currently raising investment to complete preclinical development and a planned clinical trial. 

Year Founded
2013
Biotech Phase of Development
Technology Overview
Immunotherapy, Oncolyics for Cancer
Supporting Metrics or Evidence
Comparative Live Animal Data
Current Investors
Private
IP Status
PCT Application
Recent Milestones
Seed Funding Round Completed
Management Team Highlights
Experienced Regulatory, Scientific, Medical and Development Experts within our Field
Kurt Rote
CEO 
BIO

Graduated from Duke in three years while studying Biomedical Engineering and working part-time. Hands-on lab experience using viral vectors to deliver genes to cells. MBA from IMD, a one year program in Lausanne, Switzerland. International network and experience including strategy, business development, project management, product development and start-ups.

Westwood & Wilshire LLC United States

Westwood & Wilshire is a premier provider of executive search services to the Pharmaceutical, Biotechnology, Medical Devices and Diagnostics sectors.  Services include:

-Direct Hire Executive Search
-Interim Executive Search and Consultant Placement
-Board of Director and Advisory Group Development

Our clients range from Venture Capital-backed portfolio start ups to Fortune 500 Big Pharma. Our success encompasses executive level placements across Clinical, Medical, Regulatory, R&D, Quality and Commercial.

Alan Cullen
President 
Michael Cane
Executive Recruiter 

WuXi AppTec

Joe Vacca
Head of Early Success Sharing Partnerships 

WuXi Venture Fund United States

WuXi Venture Fund is the corporate venture arm of WuXi AppTec, a multinational CRO based in Shanghai China with multiple offices across China and the United States. The fund makes equity investments into technology and life science companies to enhance or leverage WuXi AppTec's platform capabilities. The investment size will be varied based on a case-by-case basis. The firm invests in life science companies across the globe with an emphasis in China and the US.

Alexis Ji
Principal 
Sofie Qiao
Managing Director 

Xalud Therapeutics, Inc. United States

Xalud Therapeutics is developing novel, non-opioid therapies for the treatment of neuropathic pain and osteoarthritis. Our lead product, XT-101, has shown exceptional efficacy in the leading rodent models of pain and in canine patients with neuropathic pain and osteoarthritis. XT-101 has an excellent safety profile -- it does not cause sedation, dizziness, numbness, addiction or tolerance.  7 and 28 day GLP toxicology studies have been completed with excellent results.  Xalud intends to file an IND for a Phase I/IIa trial in mid-2015 and, pending funding, initiate clinical trials thereafter.

Xalud's approach to treating pain is fundamentally different than conventional approaches. XT-101 causes the body to produce the natural anti-inflammatory IL-10.  In neuropathic pain, the use of this broad spectrum anti-inflammatory reduces inflammation around the spinal cord and reduces aberant pain signaling.  In gold-standard rodent models, a single injection of XT-101 completely eliminates neuropathic pain for 12 weeks.  We have also tested XT-101 in canine patients with severe osteoarthritis that has been resistant to standard treatments.  In these patients, XT-101 has provided long lasting pain relief resulting in dramatically increased mobility and activity levels and increased joint flexibility.

To date, Xalud's efforts have been supported by over $6 million of grant funding from the NIH, the DOD, and disease foundations.  We seek to raise $6 to $10 Million to fund our initial clinical trial or trials.  These will be placebo controlled Phase I/IIa trials in actual patients.  Because XT-101 has an extended duration, we expect that these trials will provide the safety, efficacy and biomarker data necessary to support a robust Phase II program.

Year Founded
2009
Biotech Phase of Development
Technology Overview
XT-101 is a proprietary plasmid DNA encoding for the natural, broad spectrum anti-inflammatory IL-10
Alliance & Collaborations
Xalud has received extensive support from the NIH and the DOD
Supporting Metrics or Evidence
In leading models of pain, a single administration completely reverses neuropathic pain for 12 weeks. Similar results have been observed in canine patients with osteoarthritis and neuropathic pain.
Current Financing Needs
$6MM to $10MM
Current Timeline
An IND for a Phase I/IIa trial will be filed in mid-2015.
Current Investors
Xalud is entirely grant funded and has raised over $6 MM in non-dilutive financing.
IP Status
Broad patent coverage and freedom to operate have been established
Recent Milestones
In late 2014, 7 and 28 day GLP toxicology studies were completed with excellent results.
Management Team Highlights
The Management team has substantial experience leading early stage biotech companies. Dr. Steve Collins, Xalud's Executive Chairman, has extensive experience managing biopharmaceutical companies and leading pain and CNS drug development efforts. He served as Senior Director for Global CNS and Pain at Johnson and Johnson and Chief Scientific Officer and Vice President of Medical Affairs at Ovation Pharmaceuticals (acquired by Lundbeck for approximately $963 MM). Most recently he served as Chief Executive Officer of NeuroTherapeutics Pharma, Inc., a venture-backed biotechnology company developing treatments for pain and epilepsy.
Peter Heinecke
Chief Business Officer 

Xeris Pharmaceuticals, Inc. United States

Xeris is a clinical-stage pharmaceutical company developing patient-friendly injectable drugs for various indications with an initial focus on diabetes. The current paradigm for many injectable drugs is to design formulations for delivery in water-based systems.  However, the presence of water is problematic because it actively degrades many molecules often preventing drug products from being packaged for use as a “ready-to-use” solution.  Xeris' patented and patent-pending XeriSol™ and XeriJect™ formulation technologies are transformative in their elimination of water. By replacing water with non-water, bio-compatible carriers already used in other FDA-approved drugs, Xeris solves a number of problems adding significant value to existing injectable drugs and to new drugs in development.  This technology is already being validated with the development of a non-aqueous glucagon formulation that has shown 24 months of room-temperature stability in solution and very positive safety and efficacy in a Phase 2 clinical study. While this product and other glucagon products are being developed and $20M has been raised to support this development, Xeris is seeking to spinoff its earlier stage non-glucagon assets and obtain funding (both equity and non-dilutive) to support these projects.  More specifically, these projects include the development of a non-aqueous, auto-injectable diazepam to replace the current diazepam rectal gel for treatment of epileptic seizures and a non-aqueous, intradermal auto-injectable epinephrine to replace the current, antiquated EpiPen.  

Year Founded
2005
Biotech Subsector
Biotech Phase of Development
Technology Overview
Non-aqueous (no water) injectable formulations
Supporting Metrics or Evidence
Stability data, preclinical data, clinical data, FDA interactions
Current Investors
Large family offices and high net worth investors from the pharma industry
IP Status
3 issued patents and 14 additional applications pending
Dr Yash Sabharwal
Dr Yash Sabharwal
LinkedIn logo Chief Operating Officer 

Yuzu Labs United States

Yuzu Labs, based in Silicon Valley, is a research startup that aims to make clinical, behavioral, and social research more accessible, easier, faster, and cheaper. We've recently launched a private beta of our initial product named StudyPages. Researchers can use this web application to quickly set up a dedicated webpage for their studies, share with target communities, and track signups. Please visit the site to learn more: https://studypages.com
Year Founded
2014
Service Provider Type
Eron Villarreal
Eron Villarreal
LinkedIn logo Co-Founder 
BIO

Eron holds a computer science engineering degree and has broad experience in Silicon Valley startups spanning search (Inflection), mobile advertising (InMobi), electronic medical records (drchrono), and medical device development (Scanadu). At Yuzu Labs, Eron manages all things tech with a passion for quality, teamwork, and technology driven problem solving. After college, he lived in Japan for 5+ years, where he built a new life from scratch and became a hybrid of American and Japanese values.

I crave hard problems, believe that people united by a goal can change the world, work tirelessly for something I believe in, and am an optimist with no fear, despite the odds, as everything works out in the end.

Koen De Lombaert
Koen De Lombaert
LinkedIn logo Co-Founder 
BIO

Koen holds a MD (Catholic University Leuven, Belgium) and a MBA (Johns Hopkins University) and worked in lifesciences, bioinformatics, business development, marketing, and product management in academia, startups, and at Roche Pharmaceuticals. Koen enjoys technology and UX design and builds wireframes for new product ideas. His passion for science and entrepreneurshipmade him move stepwise from Belgium to the West and he calls Silicon Valley now his new home.

Zcube | Research Venture

Z-Cube invests strategically in technologies that benefit Zambon’s pharmaceuticals and API chemical businesses. 

Within the therapeutics sector, Z-Cube is interested in new technological platforms that enable Zambon’s therapeutic innovation (Z-Cube does not make developmental-stage investments in new chemical entities, and as Zambon only markets small molecule therapeutics, technologies related to biologics are not of interest). This includes drug delivery innovations, and other enabling technologies for therapeutics that do not have to undergo the full therapeutic approval process in order to reach the marketplace. 

Z-Cube is also interested in diagnostics, particularly point of care diagnostics, companion diagnostics and other diagnostics that are used alongside a therapeutic intervention, and diagnostics that can be used in preventative care or to lower overall healthcare costs. Zambon is also interested in diagnostic technologies used to monitor a chronic condition. 

Zambon’s therapeutic focus areas are respiratory diseases and pain (particularly chronic pain), and the firm is also interested in CNS disorders and women’s health (encompassing osteoporosis and rheumatoid arthritis in addition to ob/gyn). However in the diagnostics sector, Zambon is interested in all indications. 

Zambon is additionally interested in digital technologies that enhance communication in the healthcare space, particularly between doctor and patient or between general practitioners and specialists. This includes EMR and telehealth technologies, and devices that transmit information wirelessly. 

Zambon is also interested in innovations in high-tech chemistry, including purification of APIs, advanced crystallography, and novel custom synthesis.

Andrea Mills
Lorenzo Pradella