Solomon Babani

Covance

John Babcook Canada

Kairos Therapeutics has developed a proprietary next generation antibody-drug conjugate (ADC) platform based on novel toxin, linker and site-specific conjugation technology. Kairos has demonstrated superior pre-clinical in-vivo efficacy over T-DM1. Further pre-clinical studies demonstrate Kairos’ ADCs have superior tolerability and therapeutic index, compared to other leading platforms which may lead to greater clinical efficacy. Through key partnerships, Kairos is developing a novel therapeutic pipeline and is out-licensing its ADC platform to companies seeking access to state-of-the-art technology.  

Year Founded
2014
Biotech Subsector
Kairos Therapeutics
President & CSO 

Jamie Bacher

Pareto Biotechnologies
Founder & CEO 

Ibraheem Badejo

Johnson & Johnson (J&J) was founded in 1886 and is based in New Brunswick NJ with an Innovation Center in Cambridge MA. The firm invests in a variety of fields within the life science sector including medical devices. J&J?s medical device investments are highly varied in both size and structure, the structure may involve milestone payments or may be an equity investment. J&J is interested in early stage medical device companies located globally.

Johnson & Johnson (Medical Devices)
Senior Director New Ventures 

Meaghan Bailey United States

NSF Health Sciences offers clinical, regulatory, and quality consulting services across the total product lifecycle for innovative medical device, pharmaceutical, and biotechnology companies.  We specialize in helping companies balance FDA and worldwide regulatory requirements with their business needs. 

NSF Health Sciences

Mr Armen Bakirtzian

Intellijoint Surgical
LinkedIn logo CEO 

Linas Balaisis United States

Healthcare Software focusing in on Mental health & Addictions. The main goal is to place these individuals on a path to recovery.

TREAT product line is commercially available as an EHR serving the unique needs of community behavioral health, rehabilitation, and other community-based providers. The design of our system is centered on a client-centered recovery model principle with best practice assessments linked to an interdisciplinary plan of care which is at the core of our methodology. TREAT’s modules create a record of client care that functions at multiple levels and builds upon itself. From assessments, to care planning, to documentation, to decision support, TREAT provides an integrated solution centered on client care.

Assessment Tools

Our TREAT product has a catalog of over 120 different assessment tools, and can be customized to include new tools upon request. Assessments are linked with our Interdisciplinary Plan of Client Care (IPCC) and Progress Notes modules to offer a truly integrated approach to patient care.

Website:
www.treatehr.com
Year Founded
2012
Main Sector
Medtech Subsector
Medtech Phase of Development
Technology Overview
Our TREAT product has a catalog of over 120 different assessment tools, and can be customized to include new tools upon request. Assessments are linked with our Interdisciplinary Plan of Client Care (IPCC) and Progress Notes modules to offer a truly integrated approach to patient care. TREAT includes such noteworthy tools as the New York Common Assessment of Need (NYCAN), the ADAT tool suite (Addictions assessments), the PHQ-9, we will shortly be incorporating the Patient Activation Measure (PAM-13), and we uniquely offer the Metabolic Health Monitor, which tracks metabolic functioning for clients on second-generation antipsychotic medications.
Alliance & Collaborations
GSI health
Supporting Metrics or Evidence
TREAT’s IPCC and Progress Notes modules offer integrated Best Practice Guidelines (BPGs) developed in partnership with researcher Dr. Diane Doran at the University of Toronto. This module incorporates best practice guidelines into the care plan, delivering vital, pertinent guidelines to care givers at the point in time when they are making treatment decisions. The BPG options are available as canned-text which is accessed automatically using an incremental search feature. This database can be managed by the administrator, so any updates or organization specific best practices can be incorporated directly into the TREAT system. The standardization provided by this feature offers allows clinical decision support professionals to report against these text fields and improve the organization’s practices to achieve better client care. For example, these reports can help professionals to measure the effectiveness of certain interventions in the treatment of specific issues.
Current Financing Needs
$1Million
Current Investors
friends and family
IP Status
Treat as Clear
Recent Milestones
implementation with one of largest US providers
Management Team Highlights
Peter Catford, President Peter has been active in the healthcare computer consulting and management industry for over 30 years. Peter Co-founded a consulting company in the 1976 that provided technical consulting expertise to fortune 500 companies. The company later transitioned into Baxter Corporation’s healthcare division, where he was responsible for managing a technical group of 28 professionals. The group was responsible for software product development, implementation and installation in Canadian hospitals and healthcare institutions. Peter then moved to co-develop a strategy to integrate the information services departments between Mount Sinai Hospital and The Toronto Hospital. In 1997, Peter founded HInext Inc. to offer consulting and software development primarily focused on information healthcare solutions to healthcare institutions and hospitals across Canada. During the first few years of the business, Peter took an active role as the CIO in the Center for Addiction and Mental Health (CAMH). Peter managed the business information and intelligence systems and established a strategy and the architecture for electronic health record implementation at CAMH. Currently, Peter continues to lead and manage HInext and is committed to growing the company into a North American leader in healthcare Information Systems. Linas Balaisis CA, CPA, CFO/COO Linas is responsible for the financial matters and general operations of HInext. Linas is well versed in accounting and marketing matters. He got his CA designation at Ernst & Young. Linas held various financial, tax and operational roles throughout his career. Most recently he lead all marketing activities for Toyota in Canada for Toyota, Lexus and Scion Divisions. Linas is also a direct investor in Hinext. Peggy Lucas, Senior Sales Director Peggy is responsible mainly for Business Development at HInext. Peggy has been instrumental in getting new clients for the firm and has generated north of $3 million in sales for the firm over the last couple of years. Peggy is responsible for responding to RFPs, communication with clients and creating partnership channels. She is spearheading the expansion into the US market and has signed a significant US distributor agreement that has generated substantial traction for the Company in the US Peggy has a Masters in Development studies from the London School of Economics.
HInext LLC
CFO/COO 

Dr Alcide Barberis Switzerland

Humabs BioMed is a profitable Swiss biotech company that is discovering and developing nature-selected human monoclonal antibodies using proprietary platforms. 

Humabs is currently focusing on the development of human antibodies to fight infectious diseases. Additional indications are being targeted at the discovery research stage.

Humabs has already achieved four major licensing deals with Pharmaceutical companies generating significant revenues in the form of near term revenues, as well as a stream of longer term milestones and royalties. Two of these programs are in clinical development phases.

Humabs is seeking additional investments to allow the company to bring selected programs into clinical research on its own, thus significantly increasing the added value.

Website:
www.humabs.com
Year Founded
2010
Biotech Subsector
Biotech Phase of Development
Technology Overview
Unique technology platform and know how allowing selection of monoclonal antibodies generated from immortalized human memory B cells, plasma cells or naïve B cells. Specialized in identifying, isolating, characterizing and producing the best fully human antibodies from the best human responders (antibodies of winners). Focused on infectious diseases, in which there is an acute need for new products. Additional indications include inflammatory diseases and cancer.
Alliance & Collaborations
With global Pharma companies
Current Financing Needs
Humabs is seeking additional investments to allow the company to bring selected programs forward to the more advanced drug development stages of clinical research, thus significantly increasing the added value.
Current Investors
Private
IP Status
Granted patents on technology and granted patents + applications on mAb products
Dr Alcide Barberis
Humabs BioMed SA
LinkedIn logo President & CEO 

Randy Barko

Hub Angels Investment Group is an angel group that was founded in 2 and is based in Cambridge Massachusetts. The firm manages a fund structure and recently closed its 4th fund making the total AUM of the group around $4 million. The firm makes investments ranging from $25 to $5 in equity for companies that are at least 12 months old. The firm makes investments ranging from four to eight years and prefers to invest in companies whose valuation does not exceed $1 million. Hub angels plans on making approximately 3 allocations over the next 6-9 months with stated interest in diagnostics and medical device companies.
Hub Angels Investment Group
Member 

Bob Barrett United States

Cavidi is a Swedish based diagnostic company that has developed a novel method for measuring HIV viral load in patients recieving anti-retroviral therapy for treatment of HIV. Viral load is a critical indicator of the effectiveness of HIV therapy, and has been the standard of care in the developed world for many years. Just recently the World Health Organization (WHO) updated its recommendations to include viral load for patients in the developing world where the vast majority of HIV patients exists, and a large influx of international funding has significantly increased aceess to HIV drugs. The Cavidi method is novel in that it measures the viral enzyme reverse transcriptase (RT), and not viral nucleic acid (RNA) by polymerase chain reaction (PCR). The Cavidi method is not subject to the logistical challenges of PCR such as contamination risk. The Cavidi RT assay is much less expensive and can be performed in labs that lack the sophisitication to perform technologies such as PCR. Therfore, the Cavidi assay significantly improves access to this vitally important technology. For the past several years a manual version of the Cavidi technology has been utilized in laboratories in the developing world. The performance of the assay has been validated vs the industry leading PCR methods in many peer review publications. The company is now seeking funding to develop an automated version of the assay that will make it more widely adaptable to many laborartories. 

Website:
www.cavidi.com
Year Founded
2007
Biotech Subsector
Medtech Subsector
Biotech Phase of Development
Technology Overview
Cavidi's novel IVD technology uses Reverse Transcriptase(RT) as a marker for measuring replication competent HIV in blood (HIV viral load). Measuring viral load in HIV patients receiving anti viral therapy is now a global World Health Organization recommendation. Unlike PCR tests, Cavidi's RT assay requires minimal resources & lab footprint, can measure all subtypes of HIV, and at half the cost or less of PCR tests. The technology has been proven in over 400,000 tests in 50 markets worldwide.
Alliance & Collaborations
• Johns Hopkins School of Medicine, Uganda • Burnet Institute, Australia • University of Maryland School of Medicine IHV (Institute of Human Virology) • Karolinska Hospital, Sweden • SIDA (Swedish International Development Cooperation Agency) • Royal Free Hospital, London, UK • Harvard AIDS Institute Partnership, Botswana- • New York University School of Medicine, Kenya • Swedish Institute for Infectious Disease Control, Sweden • Virus Reference Depart
Supporting Metrics or Evidence
The Cavidi ExaVIr Load assay has been widely cited in peer review publications, and favorably compared to industry standard PCR technology. In addition to routine HIV viral load measurement, the Cavidi RT assay has demonstrated favorable performance vs. industry standard PCR for early infant HIV diagnostic (EID) market. ExaVir™ assay showed excellent concordance with real-time molecular assays Abbott M2000sp and Roche Cobas TaqMan...Journal of Clinical Microbiology 47(10): 3266-3270
Current Financing Needs
Development project completion 2015 $7M + 2016 $3M =$10M Global product launch 2016 $3M + 2017 $2M=$5M
Current Timeline
Next generation of fully automated HIV viral load test development project started in 2102. Prototype 1 and 2 now working. OEM selected Q12015, validation and verification of final design Q22015, Distribution Partner selection by Q22015, pre-series Q42015, serial production start Q12016, and CE Registration Q22016. Cash flow positive 2017.
Current Investors
Two private US investors hold majority interest
IP Status
IP is strong and broad covering key aspects of the technology methods with over 100 international patents in five patent families.
Recent Milestones
• Awarded SWECARE Export Award by Swedish MOH May 2013 • Supply Agreement signed with Load Zero Foundation in June 2013 • Presentation at UN Global Health Impact Forum May 2014 • TECH20 award as top 20 (2%) of 800 startups in Sweden June 2014 • UNITAID grant LOI accepted (3/12) June 2014, Full Application grant pending Dec. 2014 • POLS/One Technology evaluation meta study (2/2014) ranks Cavidi ExaVirLoad with top global diagnostic comp
Management Team Highlights
Experts in diagnostic technology development covering: Clinical Assay Chemistry, Devices, Instruments, Software, System Integration, QA & QC, Regulatory Strategy. Commercial scale up of new technologies in global markets with focus on emerging markets in Africa and Asia. Capital raising for start up and early stage companies.
Cavidi
Global Head, Business Development