Julia Hill
Bionic Vision Technologies is the commercial entity which holds license to the patents around technology developed by Bionic Vision Australia.
Bionic Vision Australia brings together Australia’s leading experts in medical bionics to develop a bionic eye to restore vision to people with retinitis pigmentosa and age-related macular degeneration. A prototype device has been successfully implanted into three patients for two years demonstrating outstanding safety and efficacy.
Our capabilities which differentiate us from competitors include:
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Novel surgical techniques providing greater safety and stability od wide view devices
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World leading, pioneering vision processing software
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Unique arrangement and stimulation strategies of the electrodes
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Unique diamond electrode encapsulation for the high acuity device
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World leading psychophysics laboratory for assessing functionality of the devices
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Unprecedented expertise and proven track record in preclinical studies
Our development portfolio consists of wide view devices which aim to increase mobility and independence of patients and a high acuity device which will allow patients the ability to read large letters and recognise faces
Bionic Vision Technologies
Johanna Holldack
Telormedix SA
CEOChris Hollowood
Syncona Partners, founded in 2012, is an evergreen investment firm based in London, UK. The firm is an independent subsidiary of the Wellcome Trust who invested the initial £200m capitalization. The firm is mandated to invest in companies with the potential to make major breakthroughs in healthcare. The investment size will usually range from £1M – £20M per company. The firm seeks to create sustainable, profitable businesses, to support them with capital over the long term, for the benefit of patients, and to hold an ownership position to create value for the Wellcome Trust. The firm is actively screening new investment opportunities.
Syncona Partners
PartnerCarl Horn
JBI is a Midwest-based biotechnology company driven to develop a new class of therapies to treat patients with Alzheimer’s disease and other neurodegenerative diseases.
JBI’s unique approach is able to lower the production of Amyloid Beta (Aβ), phosphorylated Tau (pTau) and toxic intracellular Aβ aggregates. Our passion is to develop a therapy to restore the patient’s lifespan and improve patient quality of life.
JBI is focused on further developing its lead compound, JBI-009, based on the strength of compelling preclinical safety and efficacy results to date.
JBI’s approach represents a new wave in thinking about the treatment of AD. Currently available drugs treat disease symptoms, rather than its suspected cause, and do so with limited success. Most drugs in late-stage clinical development are attempting to address a likely cause of the disease, the accumulation of Aβ, by potently inhibiting the enzyme responsible for Aβ production. As this enzyme has other important biological functions, this approach has seen early failures because of unacceptable side effects. JBI's approach is unique in that it modulates the production of this enzyme rather than inhibits its activity. JBI’s approach is expected to restore enzyme activity and Aβ production to normal levels with a favorable safety advantage.
JBI’s technology is also unique in that it targets cellular machinery within the Endoplasmic Reticulum (ER). Most drug developers have focused on modifying activity that occurs either on the cell membrane or within the cell nucleus or cytosol. JBI is one of the first, if not the first, to successfully target activity within the ER. The discoveries employed by JBI have produced a lead compound that affects the enzyme responsible for controlling the rate-limiting step in Aβ production, penetrates the blood brain barrier, and shows no toxicity in IND feasibility safety studies. In addition, work has begun on next generation compounds. This ER-focused approach provides platform potential for future therapies to treat additional significant unmet medical needs.
Jace Biomedical, Inc.
CEOBrian Horsburgh
NeuroNetworks Fund
TrusteeBrian Horsburgh
Immunova is a startup with an IP portfolio licensed from Yale and the Johns Hopkins Universities.
Immunova's technology platform has a unique capability to deliver one or more drugs to the tumor/disease microenvironment. The drugs can be proteins, small molecules or nucleic acids. The delivery platfrom has demonstatable advantages over other delivery systems. The technology has applications in oncology and inflammation.
The company's lead asset is positioned in oncology. IMM-01, consists of two drugs that (a) undermine the tumor micorenvironment and (b) increase anti-tumor cell mediated immunity. This asset is capable of curing mice of metastatic disease. Further, it significantly enhances the activites of immune checkpoint inhibitors. It is non toxic.
The company is seeking investment and R&D partners. Immunova has defined the path to a Phase I/IIa multidose trial which could initiate within 15 months of funding. Immunova is also seeking partners who wish to validate this platform in oncology and inflammation.