David Jonas United States

JVC Investment Partners is a private investment firm that was founded in 2000 and is based in Chicago, Illinois. The firm focuses on investments in the healthcare industry. The investment size can vary greatly and is very flexible depending on each company’s needs. The firm provides venture capital and growth capital to healthcare companies. For early-stage investments, the firm targets companies that provide solutions for hospital acquired infections, medication errors, healthcare system operational efficiency enhancements and cost reductions, and chronic disease management, and it typically invests equity or convertible preferred equity in post series A rounds. For growth investments, the firm targets companies with compelling products and strong position in niche markets and with an EBITDA in excess of $2 million. The firm primarily invests in companies based in US.

JVC Investment Partners
Founder, President & CEO 

Jonathan Jonas United States

JVC Investment Partners is a private investment firm that was founded in 2000 and is based in Chicago, Illinois. The firm focuses on investments in the healthcare industry. The investment size can vary greatly and is very flexible depending on each company’s needs. The firm provides venture capital and growth capital to healthcare companies. For early-stage investments, the firm targets companies that provide solutions for hospital acquired infections, medication errors, healthcare system operational efficiency enhancements and cost reductions, and chronic disease management, and it typically invests equity or convertible preferred equity in post series A rounds. For growth investments, the firm targets companies with compelling products and strong position in niche markets and with an EBITDA in excess of $2 million. The firm primarily invests in companies based in US.

JVC Investment Partners
Partner 

Rick Jones

Broadview Ventures is a Philanthropy Venture firm that was established by the Leducq Family Trust in 28 and dedicated to accelerating the translation of new and innovative programs in the CV and stroke areas. The firm is based out of Boston MA but is geographically agnostic in its investing. The firm makes equity and convertible note investments of approximately $1 million into companies that are targeting cardiovascular and neurovascular diseases. The firm invests in privately held companies at both the seed and venture stage and is currently invests in 4-5 companies per year. The firm operates under an evergreen structure and is constantly seeking new investment opportunities. While the firm will consider investments around the globe Broadview is keen to add companies based in Europe to its portfolio. Broadview has previously invested in the US Europe and Israel.
Broadview Ventures
Director 

Alan Jones Switzerland

Biotechgate is a global, comprehensive, Life Science database encompassing the Biotech, Pharma and Medtech industries.
There are over 30,000 company profiles available on Biotechgate with information such as pipelines, technologies, financing rounds, management details, licensing opportunities and deals.

Year Founded
2003
Biotechgate

David Joseph United States

Avisa Pharma™ Inc., (AVISA) is a Point Of Care, In-Vivo Platform Technology Company With An Innovative, Integrated System For The Rapid Detection And Monitoring Of Respiratory Diseases. A paradigm shift away from lab based In Vitro testing; an In Vivo, point of care, breath test that measures the whole lung, live organisms, not a single culture sample in a petri dish or PCR;for non sputum producers - the only test that can detect lung bacteria without a sputum culture; A razor/razorblade Model to Drive Rapid Market Penetration and Growth.

Focused initially on respiratory health, the clinical study strategy is to pursue fastest route to regulatory approvals, the detection of Tuberculosis (TB), followed by Healthcare Acquired Pneumonia (HCAP), Ventilator Associated Pneumonia (VAP), Cystic Fibrosis (CF) and COPD. These applications have the potential to help save millions of lives and millions of dollars in healthcare costs each year, and a multi billion $ market opportunity.  

$6 million Series A1 Preferred round underway, $4 million received from current investors exercising preemptive rights. Q1 2015 Avisa will be launching a 40 patient pilot TB study in South Africa.

Year Founded
2011
Main Sector
Medtech Subsector
Medtech Phase of Development
Technology Overview
The AVISAR Systemâ„¢ is drug device combination comprised of AV-U13, an inhalable urea solution, the portable AVISARâ„¢ Spec Laser Spectrophotometer and the Aeroneb Solo nebulizer. The AV BreathTestâ„¢ allows clinicians to assess the presence or absence of bacteria in the entire lung, non-invasively, within minutes and monitor therapy for better antibiotic stewardship. A paradigm shift away from lab based In Vitro testing. An In Vivo, point of care, breath test that measures the whole lung, live organisms, not a single culture sample in a petri dish or PCR. For non sputum producers - the only test that can detect lung bacteria without a sputum culture.
Alliance & Collaborations
None
Supporting Metrics or Evidence
Pre-clinical, Clinical
Current Financing Needs
Series A1 $6 million, $4 million raised from current investors
Current Timeline
PMA in 2017
Current Investors
Venture fund, private equity investors
IP Status
Issued and Pending Patents
Recent Milestones
Positive Clinical Data in Proof of Concept in Cystic Fibrosis clinical study
Management Team Highlights
CEO 35 years, four successful exits
Avisa Pharma Inc.
President - CEO 

Jeff June United States

Ischemia Care (ISC) is a clinical stage, capital efficient, venture capital backed, diagnostic laboratory company commercializing ISCDX, a blood test for cause of ischemic stroke (including atrial fibrillation or “AF”), leading to timely diagnosis and treatment, resulting in hospital cost savings and improved patient outcomes. ISC is executing on the Biomarkers of Acute Stroke Etiology (BASE) study , clinicaltrials.gov identifier NCT02014896 to support clinical adoption as an LDT through a company owned CLIA laboratory. ISC's initial focus is on the 40% (320K annually) ischemic strokes which are diagnosed as unkown cause (or "cryptogenic") as these patients typically are undertreaked and at a high risk for recurrence.

Stroke is the third leading cause of death worldwide with 20M annual events. In the US, there are 800K strokes, of which 195K are recurrent. Despite advances in imaging, cardiac monitoring, patient history assessment, and clinical examination, in 40% of ischemic strokes, the cause is unknown (or “cryptogenic”) leading to high recurrence and death.  There are no blood tests for cause of stroke. The identification of cause will change outcomes per Stroke Guidelines by adoption of “cause based” treatment regimen to prevent a more massive, debilitating, and costly recurrence. For example, identifying “undetected” AF in cryptogenic patients provides a 60% risk recurrence reduction.

Website:
www.iscdx.com
Year Founded
2009
Biotech Subsector
Biotech Phase of Development
Medtech Phase of Development
Technology Overview
Blood test for cause of stroke. The test (called ISCDX) detects immune responses by RNA expression related to causes of stroke, including AF, within minutes of event. ISCDX is ordered by a clinician at a hospital after a stroke has occurred, a tube of blood is drawn, sent to the ISC CLIA laboratory, results are reported to the physician during patient hospitalization , and paid through the hospital under existing reimbursement (DRG) codes. ISCDX may reduce cost by $7,000 per patient and increase hospital revenue.
Alliance & Collaborations
Medronic, Affymetric, Cleveland Clinic, MUSC, Allegahany Health Network, Albert Einstein Medical Center, UCLA.
Supporting Metrics or Evidence
14+ years, 600+ patients of data, 5 patents, $5M Federal Funding (pre licensing by ISC), and publications in major peer reviewed journals. Previous research has demonstrated sensitivity/ specificity > 95%. ISC reached milestones faster and with less investment than comparable exits.
Current Financing Needs
ISC is raising a $5M series C at $6.5M pre money, with $2.5M closed. ISC previously raised $2.3M in equity and $1.4M in non dilutive funding, further demonstrating commercial and technical merit.
Current Timeline
ISC is following proven commercial pathway. The BASE clinical trial will serve as a final clinical validation and build sales channel to commercially offer the ISCDX test through the company CLIA laboratory. This strategy is similar to companies such as Veracyte and Foundation Medicine (both 2013 IPOs).
Current Investors
Broadview Ventures, Cleveland Clinic (GCIC grant), Queen City Angels, Ohio Third Frontier, Accelerant Fund, and private individuals.
IP Status
5 patents in various stages of prosecution, international filings as well.
Management Team Highlights
Proven management team and board (2 IPOs, multiple exits, past president of AHA, chief of cardiology at Stanford, 4 VC directors), KOLs in the field of stroke (including author of the Stroke Guidelines), strategic support (Affymetrix, Medtronics), and leading stroke center directors.
Jeff June
Ischemia Care
LinkedIn logo CEO & Founder