AbCellera Canada

AbCellera has developed a next generation technology for the analysis and screening of naturally derived immune repertoires. This platform uses high-throughput single cell analysis to enable the discovery of naturally derived monoclonal antibodies with unmatched speed, efficiency, and assay flexibility. By eliminating the need to culture cells this approach may be applied to antibody discovery from non-traditional host species, including rabbits and llamas, and achieves industry-leading capabilities in isolating antibodies from patient samples, with applications in infectious disease and autoimmunity.

AbCellera is engaged in antibody discovery projects with early partners, including biotech and pharma companies, and is also initiating internal programs aimed at using immune profiling for target identification and lead molecule discovery.

We are looking for Series A financing from strategic investors, as well as new partnerships with antibody drug development companies.

 

Dr Carl Hansen
Dr Carl Hansen
CEO & President 

AdeTherapeutics Inc Canada

“AdeTherapeutics’ approach has potential to become standard of care,” says Dr. Greenberg, Vice Chair Obs & Gyn at Brigham and Women’s Hospital and Associate Professor at Harvard Medical School.

Our platform technology which KOL’s have pointed out as a game changer in the area of preventing post operative fibrosis, is poised to create significant value.  The pipeline contains a phase II drug for prevention of post operative fibrosis following pelvic and abdominal surgeries, med devices (collaboration with DSM Biomedical) for spinal surgery and additional opportunities in orthopedics.  

The Company has built a world class team, utilized a capital efficient, highly targeted and focused approach and brought on the necessary strategic partners to bring first-in-class products to the market and establish standard of care for millions of surgeries worldwide.Key value propositions:

•             useful in more procedures than current medical devices

•             significant higher efficacy vs market comparators

•             attractive safety profile & accelerated regulatory pathway

Key Milestones achieved:

  • Phase II trial started
  • Key markets patents issued: USA, EU, Japan
  • Efficacy shown in different tissues areas
  • Two peer reviewed publications in 2014

 

Biotech Subsector
Biotech Phase of Development
Medtech Phase of Development
Technology Overview
. Key publications in 2014 by leading authors in the space supports our novel cellular and molecular approach. Evitar is used at the time of surgery to correct the imbalance in the system brought on by surgical injury which triggers the cascading activation of many pro-inflammatory pathways (including TGF-Beta) that promote adhesion or fibrosis development.
Alliance & Collaborations
DSM Biomedical, Evonik Industries (Mftring) and exploring others
Supporting Metrics or Evidence
publications, preclinical data and POC reading out in early 2015
Current Financing Needs
$5-$6 million
Current Timeline
POC early 2015 for lead indication, moving second indication into the clinic by end of 2015
Current Investors
privately financed by management and board
IP Status
patents issues in major markets
Recent Milestones
phase II trial initated, USA patents issued, two key publications in 2014 in peer reviewed journal
Management Team Highlights
Significant experience in busines devleopment, marketing, clinical, regulatory and buisness development in the hospital space and med devices and therapeutics
Mr Sanj Singh
LinkedIn logo President - CEO 

Adjuvant Therapuetics Canada

Adjuvant Therapeutics Inc. is a clinical stage medical device company that is developing a system to improve the effectiveness of radiotherapy for cancer treatment. The system, called OncO2™, uses innovative technology to increase oxygen concentrations in tumours, making them more sensitive to radiation.


Poor tumour oxygen has long been known to make radiation less effective, particularly in cancers of the head and neck, where 5 year survival rates range from 17% to about 63%. The OncO2™ system allows for individual optimization of therapy to maximize the effectiveness of the radiation.


Adjuvant Therapeutics will initially focus on head and neck cancers, however the OncO2™ system can also address other types of resistant cancers such as those of the cervix and bladder.

Year Founded
2014
Main Sector
Biotech Phase of Development
Medtech Phase of Development
Cliff Ansel
CEO 

Aspect Biosystems Canada

Aspect Biosystems uses proprietary bioprinting and cell culture technologies to create high quality living 3D human tissues.  We aim to improve the pre-clinical drug discovery process by providing pharmaceutical companies and researchers with functional living tissues that better predict the human response to drugs.  Our testing platforms will enable pharmaceutical customers to identify failed drugs earlier in the development pipeline, before expensive clinical trials begin.  Aspect Biosystem’s long-term vision is to create human tissues on demand for multiple applications including cosmetics-testing, personalized medicine, diagnostics and regenerative medicine.

Year Founded
2013
Medtech Subsector
Technology Overview
Aspect has proprietary 3D bioprinting and tissue engineering technologies that enable the fabrication of complex, biologically relevant living human tissues.
Alliance & Collaborations
Multiple academic and industry collaborations
Supporting Metrics or Evidence
Multiple functional endpoints confirm biological function of the engineered tissue constructs.
Current Timeline
1st tissue product (airway) is in the process of productisation. Bioprinter development and optimisation of alternative tissue types is underway.
Current Investors
Founders, family and friends, Angels, Seed fund.
IP Status
Bioprinter PCT in place. Full patent application in September 2015
Recent Milestones
2nd place in BC Innovation Council's New Ventures competition (Sept 2014)
Mr Simon Beyer
Co-founder 

CDRD Ventures Canada

CDRD Ventures Inc. (CVI) is the commercialization vehicle of the Centre for Drug Research and Development (CDRD), Canada's national drug development and commercialization center that was founded in 2007 and is based in Vancouver, Canada. CVI seeks to advance promising drug development projects from CDRD using internal funds and through partnerships with international pharmaceutical companies, venture capital firms, biotech companies, and other funding agencies. CVI also seeks to in-license technologies from industry or non-CDRD affiliated research institutions. The firm considers both small molecule and biologic innovative technologies in virtually any therapeutic area.

Ms Natalie Dakers
President & CEO 
Mr Michael Lincoln
Chief Financial and Business Officer 

Fusion Genomics Corporation Canada

Fusion Genomics Corp (FG) is a molecular diagnostic test  development company that is introducing diagnostic kits with companion analysis software that offer superior clinical information, faster turn-around-times and ease of use for hospitals and clinical laboratories. Fusion is the first of two companies in the world to bring a validated Next Generation Sequencing (NGS) diagnostic test complete with highly secure cloud based analytical service for childhood cancers (ChildSeq-RNA SRCT) into the clinic. This test was validated in the renowned medical testing facility at the Texas Children Hospital, Baylor College of Medicine.

FG is completing development of kits for facilitating absolute diagnosis of pediatric and adult blood cancers. In addition, FG has partnered with the Royal Tropical Institute (Dutch: Koninklijk Instituut voor de Tropen; KIT) a World Health Organization reference diagnostic laboratory for infectious diseases to design the next generation of assays for the detection of infectious diseases including drug-resistant forms of tuberculosis, influenza, hepatitis and hemorrhagic fevers including Ebola.

Year Founded
2013
Biotech Subsector
Medtech Subsector
Biotech Phase of Development
Medtech Phase of Development
Technology Overview

Fusion Genomics Corporation (FG) develops molecular diagnostic tests that utilize next-generation sequencing (NGS) technologies. All of FG’s tests can be used with any of the widely adopted NGS instruments on the market. Data is analyzed using FGF’s secure FusionCloud, providing diagnosis –enabling DNA sequence information to the clinician.

Most NGS based diagnostic efforts can be divided into two categories: 1) whole genome sequencing (WGS), where the entire DNA of an individual (or a pathogen) is sequenced, and 2) target-capture sequencing (TCS), where only diseased portions of DNA are sequenced. TCS produces 1000 times less data than WGS. The expensive computational resources required for analysis of WGS data prevents it from being adopted for routine clinical use. Therefore, TCS is more suitable and appealing in frontline diagnostic environments.

TCS uses either PCR or “DNA baits” as the underlying technology to “capture” disease-specific regions of the genome. PCR-based methods suffer from limitations described earlier. FG uses proprietary Quantum ProbesTM, an enhanced form of DNA baits, in all its tests. Quantum ProbesTM allow for nearly limitless expansion of genetic targets and rapid development of new tests as well as patentable techniques that are beyond the capacity of PCR. The superior advantage of Quantum ProbeTM, coupled with FusionCloud analysis and reporting, will drive the successful adoption of the tests. 

Alliance & Collaborations
Texas Children Hospital, Baylor College of Medicine (Houston, USA), British Columbia Centre for Disease Control (Vancouver, Canada), Royal Tropical Institute / Koninklijk Instituut voor de Tropen (Amsterdam, Netherlands)
Supporting Metrics or Evidence

The Fusion Genomics team published a very well received peer-reviewed publication which demonstrated that their technology was more sensitive, accurate, rapid and comprehensive than current industry standards such as PCR and FISH.  This study can be found at here.

Current Financing Needs

 $0.5-1M to complete seed round

Current Investors

Founders, board members, family and friends.

IP Status

Patent applications are pending.

Management Team Highlights

Fusion Genomics Corporation’s team has established expertise in next-generation sequencing, diagnostic test and software development, and information technology.

Mohammed Qadir, PhD., Chief Executive Officer and Chief Scientific Officer has over 17 years of research experience; the last 10 were at the British Columbia Cancer Agency. As part of his early training, he worked with world-renowned experts in genomics and drug development and is the co-inventor of the ChildSeq assay and ChildDecode.

Greg Stazyk, Chief Technical Officer has over 20 years of experience in senior positions in the IT industry. Mr. Stazyk was the IT lead for one of Canada’s largest bioinformatics computing platform at the BC Cancer Agency’s Genome Sciences Centre (GSC). Mr. Stazyk was the senior manager at PMC-Sierra Inc. responsible for its global computer systems operation.

Brian Kwok, VP of Product Development has close to 10 years of experience in molecular biology and genomic technologies including leading edge next-generation sequencing. Mr. Kwok has worked in combinatorial drug screening and led the development of the ChildSeq assay.

Dr. Poul Sorensen MD, PhD: Board member and clinical expert. Dr. Sorensen is a world-renowned pediatric pathologist and is the Johal Chair in Childhood Cancer Research at the University of British Columbia, as well as a professor in the Department of Pathology and a Senior Scientist at the BC Cancer Research Agency (Vancouver, Canada). Dr. Sorensen is also the Chair of the Translational Research committee of the Children’s Oncology Group.

Mohammed Qadir
Chief Scientific Officer 

Fusion Pharma Canada

Fusion Pharmaceuticals is a clinical stage company committed to developing next generation precision radiopharmaceuticals for the diagnosis and treatment of human cancers with unmet medical needs.  The Company’s lead product, FPX-01, combines an alpha radionuclide with the precise targeting of an antibody to cause selective cytotoxicity of tumor cells.  FPX-01 will be entering Phase 2 clinical development in H2, 2015.

Year Founded
2014
Biotech Phase of Development
Technology Overview
The FPX-01 program represents a true theranostic approach. By leveraging its expertise in radiochemistry and biology, and utilizing different isotopes, Fusion has produced variants of FPX-01 that act as either diagnostic or therapeutic agents. For human proof-of-concept, Fusion initiated a Phase I imaging trial in Canada. Using Iodine-124 as a probe, this trial was designed to confirm that FPX-01 binds and internalizes to solid tumors expressing the receptor target as determined through PET/CT imaging. Initial results from this trial demonstrate that FPX-01 can identify metastatic lesions not previously identified through other imaging techniques. These data corroborate previous preclinical in vivo data which indicated that the radioactivity-associated with FPX-01 accumulated within tumours over several days. Following the completion of the Phase 1 imaging trial and additional preclinical studies planned for H1 2015, Fusion will file an IND in H2 2015 that will be designed to achieve breakthrough status in NSCLC. For therapy, FPX-01 will be radiolabeled with an alpha-emitting isotope. Preclinical xenograph studies, using only a single administration of isotope demonstrated tumor regression, with minimal toxicity at any dose level. It is expected that the IND-opening trial will be a Phase I/II therapeutic study in approximately 100 patients with non-small cell lung cancer (NSCLC), addressing a major unmet medical need.
Alliance & Collaborations
Ontario Institute for Cancer Research
Supporting Metrics or Evidence
Clinical and pre-clinical data.
Current Financing Needs
Series A $15M
Current Timeline
H2 2015: Phase 2 IND
Current Investors
Centre for Probe Development and Commercialization
IP Status
The FPX-01 antibody is protected worldwide via multiple granted patents. Additional combinations of delivery vehicles, conjugation/chelation technologies and radioisotope variation are routinely considered and evaluated for their proprietary nature and if appropriate, patent applications are filed. Regulatory exclusivity will extend FPX-01 protection in the US market.
Management Team Highlights
Frank Gleeson, CEO. Founding CEO of Fusion Pharma, DVLR Therapeutics, Verio Therapeutics (sold to Fate Therapeutics in 2010) and former Partner with MDS Capital Corp. Mr. Gleeson has raised over $200M in syndicated financings.
Michael Cross

Gait Tronics Canada

GaitTronics has developed a robotic patient handling system called SoloWalk. SoloWalk provides effortless mobility for frail patients which would otherwise require two or more caregivers to assist them and put the patients at risk of falling. With SoloWalk's intelligent patient driven mobile system, a single caregiver can mobilize a patient. Additionally, an automatic fall protection system supports the patient automatically if a balance loss is detected, significantly reducing the risk of injury for patients and staff.

Currently, hospitals are only providing adequate mobility for 30% of their patients. With SoloWallk, these institutions can expect to significantly increase this proportion and reduce complications associated with immobility, including: functional decline, bed sores, increased delirium and increased length-of-stay. With the potential of reducing length-of-stay by two days, there is a significant ROI for using SoloWalk in an acute care setting.

Watch a demo of SoloWalk at http://youtu.be/tIcfEsnQ4uY .

Website:
GaitTronics.com
Year Founded
2012
Main Sector
Indication
Medtech Phase of Development
Technology Overview
SoloWalk is a patient handling robot that helps frail patients get up and walk. Early mobility can significantly reduce complications associated with immobility and can reduce length-of-stay by two days.
Current Financing Needs
We are currently seeking to raise a $1.1M seed round.
Current Timeline
Product launch is targeted for early 2016.
IP Status
Pending
Recent Milestones
Initiated first clinical trial at the Ottawa Children's Treatment Centre with adolescent cerebral palsy patients.
Dr Aliasgar Morbi
Dr Aliasgar Morbi
LinkedIn logo ‎Chief Technology Officer and Co-founder 

Global Connectworks Ltd. Canada

STRATEGIC CONNECTIONS. CREATIVE SOLUTIONS. Manage your company outreach to investors and partners.

Connecting companies with the right people to build strategic alliances with global partners and investors. Supporting international life science companies in cross border corporate development, financing, investor relations and conference participation. A proven track record leveraging an extensive global network of CEOs, investors and partners into strategic alliances that support business imperatives. CORPORATE DEVELOPMENT - Connecting companies with potential investors and business development opportunities. CONFERENCE ADVISOR Program - A customized program to optimize company participation at key events and conferences to, maximize value and achieve tangible results including online partnering management and management of all conference outreach. 

Service Provider Type
Unique Capabilities

Leverage an extensive network for my clients.

Betsy Bascom
President & CEO 

Immunimed Inc. Canada

Immunimed Inc is a clinical-stage Biopharmaceutical company developing innovative egg-derived, oral potclonal antibody therapy to treat gastro-enteric infections/diseases. Our lead product IMM-001 targets super bug, Clostridium difficile, leading cause of hospital-acquired infections.

Currently is Phase II ready with remarkable clinical response in Proof on Concept multi-center clinical studies.  Phase II clinical study is planned for Q2 2015.

Year Founded
2013
Biotech Subsector
Biotech Phase of Development
Current Financing Needs

$5-6M to complete clinical development.

Current Timeline

Q1-Q2-2015

IP Status

Four patents issued and one pending

Dr Pradip Maiti
President 
Dan Zekzer
Principal