Humabs BioMed SA Switzerland

Humabs BioMed is a profitable Swiss biotech company that is discovering and developing nature-selected human monoclonal antibodies using proprietary platforms. 

Humabs is currently focusing on the development of human antibodies to fight infectious diseases. Additional indications are being targeted at the discovery research stage.

Humabs has already achieved four major licensing deals with Pharmaceutical companies generating significant revenues in the form of near term revenues, as well as a stream of longer term milestones and royalties. Two of these programs are in clinical development phases.

Humabs is seeking additional investments to allow the company to bring selected programs into clinical research on its own, thus significantly increasing the added value.

Website:
www.humabs.com
Year Founded
2010
Biotech Subsector
Biotech Phase of Development
Technology Overview
Unique technology platform and know how allowing selection of monoclonal antibodies generated from immortalized human memory B cells, plasma cells or naïve B cells. Specialized in identifying, isolating, characterizing and producing the best fully human antibodies from the best human responders (antibodies of winners). Focused on infectious diseases, in which there is an acute need for new products. Additional indications include inflammatory diseases and cancer.
Alliance & Collaborations
With global Pharma companies
Current Financing Needs
Humabs is seeking additional investments to allow the company to bring selected programs forward to the more advanced drug development stages of clinical research, thus significantly increasing the added value.
Current Investors
Private
IP Status
Granted patents on technology and granted patents + applications on mAb products
Dr Alcide Barberis
Dr Alcide Barberis
LinkedIn logo President & CEO 

ICON

Website:
www.iconplc.com
Vicki Anastasi
Senior Vice President Medical Devices & Diagnostics Research 

ideaPoint United States

Year Founded
2008
Service Provider Type
Unique Capabilities

Scout. Evaluate. Invest. Manage.

ideaPoint delivers the leading innovation management solution for the global enterprise. With ideaPoint software, you can scout, evaluate, invest in, track and manage dynamic growth opportunities – all with one secure, simple tool.

ideaPoint provides full lifecycle management of BD/Licensing and acquisition opportunities from scouting, to evaluation, to negotiation, to alliance management; while offering robust tracking and reporting capabilities. Clients include some of the world's most successful BioScience companies.


ideaPoint brings to the enterprise a comprehensive toolset and our best practices to help companies better collaborate and partner in a secure virtual environment.

With ideaPoint software, companies can tactically scout, evaluate and seize a range of growth opportunities, secure strategic partnerships, and manage critical requests, initiatives and alliances

Our solution delivers visibility and facilitates collaboration across an organization and with external partners, streamlining the flow of complex information and optimizing the unique process of each team.

With virtual team assembly and automated routing, robust tracking and on-demand reporting, the ideaPoint solution reduces administrative overhead, increases efficiency and efficacy of process, and provides a simple and intuitive user experience.

Ronnie Koss
VP - Development 
Kaitlin Sullivan
Sales and Marketing Coordinator 
Scott Shaunessy
CEO 

Iliad Ventures

Iliad Ventures is a private investment firm funded entirely by its partners that is based in New York City. The firm is looking to make equity investment into early and mid-stage life science companies ranging from $5 to 2 million initially. The firm looks to get involved in Seed and Series A Rounds. The firm could make as many as 6 investments over the next 12 months and looks to invest in companies located throughout the United States Europe and Israel.
Steve Tsetsekos
General Partner 

ImmunGene Inc.

Sanjay Khare
President & CEO 

Immunimed Inc. Canada

Immunimed Inc is a clinical-stage Biopharmaceutical company developing innovative egg-derived, oral potclonal antibody therapy to treat gastro-enteric infections/diseases. Our lead product IMM-001 targets super bug, Clostridium difficile, leading cause of hospital-acquired infections.

Currently is Phase II ready with remarkable clinical response in Proof on Concept multi-center clinical studies.  Phase II clinical study is planned for Q2 2015.

Year Founded
2013
Biotech Subsector
Biotech Phase of Development
Current Financing Needs

$5-6M to complete clinical development.

Current Timeline

Q1-Q2-2015

IP Status

Four patents issued and one pending

Dr Pradip Maiti
President 
Dan Zekzer
Principal 

Immunova LLC United States

Immunova is a startup with  an IP portfolio licensed from Yale and the Johns Hopkins Universities.

Immunova's technology platform has a unique capability to deliver one or more drugs to the tumor/disease microenvironment. The drugs can be proteins, small molecules or nucleic acids. The delivery platfrom has demonstatable advantages over other delivery systems. The technology has applications in oncology and inflammation.

The company's lead asset is positioned in oncology. IMM-01, consists of two drugs that (a) undermine the tumor micorenvironment and (b) increase anti-tumor cell mediated immunity. This asset is capable of curing mice of metastatic disease. Further, it significantly enhances the activites of immune checkpoint inhibitors. It is non toxic.

The company is seeking investment and R&D partners. Immunova has defined the path to a Phase I/IIa multidose trial which could initiate within 15 months of funding. Immunova is also seeking partners who wish to validate this platform in oncology and inflammation.

Website:
www.immunova.net
Year Founded
2011
Biotech Subsector
Biotech Phase of Development
Technology Overview
Immunova’s platform enables effective drug combination therapy. Chemically diverse drugs such as biologics and small molecules can be formulated and encapsulated in a liposome and thereby delivered systemically to a target cell or environment where each encapsulated API can be released independently in a controlled or tuneable manner using our proprietary technology. Importantly, this approach also potentiates existing or novel therapies often increasing their therapeutic index. LipoGel-TR is a hybrid platform of liposomes and PLGA nanoparticle delivery systems designed to possess the positive features of each platform while minimizing the negative aspects. Many of the building blocks required to make a LipoGel can be bought preassembled and GMP from third party providers thus shortening development timelines. We have demonstrated the superiority of LipoGels in numerous in vitro assays (drug loading and release and potency) and animal models of disease (efficacy and survival). Using our technology we have demonstrated that we can (a) direct one or more drugs to the TME, (b) increase drug synergies, efficacy and potency of chemo and immunotherapies, (c) decrease drug toxicity, (d) increase immune cell activity and (e) generate new intellectual property.
Alliance & Collaborations
The company is actively seeking partners in oncology and inflammation.
Supporting Metrics or Evidence
The technology has been published in high profile journals and the founder actively collaborates with numerous scientists at leading institutions. The Company’s initial focus is cancer immunotherapy: delivery of molecules that modulate immunity, positively and negatively, in order to undermine the tumor microenvironment and allow the immune system to keep pace with tumor evolution and thus be primed to eradicate disease. Our lead asset, IMM01: • Is targeted to and accumulates in tumors; • Encapsulated APIs are slowly released over 7 days and this can be further modulated; • Dramatically increases potency and efficacy: in a murine model of metastatic disease, IV delivery of IMM-01 results in 85% survival of IMM-01-treated mice at day 60 whereas all untreated mice, as well as mice treated with the drugs in solution, have died by day 30; • Increases immune infiltrate within the tumor which correlates with good patient outcomes • Significantly increases the potency of anti-PD1 and anti-CTLA4 mAb therapy in a mouse model of metastatic disease supporting published MoA studies • Is not toxic; there are no signs of renal, hepatic, bronchial, RBC or leukocyte toxicity when IMM-01 is administered to mice at high doses.
Current Financing Needs
Immunova is seeking $8-10M to fund operations for three years and including a phase I/IIa clinical trial
Current Timeline
Pending financing, IMM-01 is ca 15 months from a Phase I/IIa clinical trial
Current Investors
Angel-backed to date
IP Status
The company has licensed 4 granted and 3 pending patents
Recent Milestones
Q3 2014 • Demonstration of synergy with checkpoint inhibitors • New patent filed • Patent granted • Academic founder noted as a bioentrepreneur to watch by Nature Biotechnology Q4 2014 • First phase technology transfer to CMO • Identified lead clinical trial site and PI • Determined drug needs for clinical trial • Regulator engaged for ‘preIND meeting’
Management Team Highlights
The Company has recruited an impressive team that has an established and successful record of building companies. The management, advisors and scientific founders have an established network of both pharmaceutical and medical contacts and extensive experience running biotechnology firms and executing clinical trials. For reference, the following biotech startups founded/managed/invested in by Immunova Management or Advisors, were acquired prior to FDA approval: • Neurovir Therapeutics, Inc. – Acquired by MediGene AG for $42M • Nurel Therapeutics – acquired by DyaMid AB (undisclosed) • Proximagen plc. – Acquired by Upsher Smith for $550M • PharmaGenics Inc. – acquired by Genzyme for $28M • Prostagen– acquired by Cytogen (undisclosed)
Brian Horsburgh

Immusoft Corporation United States

Immusoft’s mission is to develop a breakthrough platform for delivering targeted medicines — programming a patient’s own cells to become miniature drug factories.

Our technology instructs a patient's cells to constantly secrete gene-encoded medicines (biologics). It will enable new treatments by solving current delivery limitations and production challenges. We are initially targeting orphaned diseases. 

Immusoft’s platform can program cells to continually produce and secrete therapeutic proteins and rare antibodies that have been impossible to elicit with a vaccine. This approach makes possible treatments that are otherwise impractical due to short halflife, injection site reactions, production challenges or a small market size. It offers many of the benefits of traditional approaches and modern gene therapies with less risk and greater control.

Immusoft has received grants from the National Institutes of Health and Peter Thiel's Breakout Labs as well as support from private investors, including the former head of preclinical development at Seattle Genetics. We have an exclusive license option on our core technology from Caltech and have filed two additional patents covering our extensive modifications to the technology.

ISP technology could replace a lifetime of infusions with a patient’s own drug-producing cells.

Website:
www.immusoft.com
Year Founded
2009
Biotech Phase of Development
Technology Overview
Turning patients' cells into drug factories
Alliance & Collaborations
Fred Hutchinson Cancer Research Center, Discovery Genomics, Inc, University of Minnesota, The Ragon Institute, University of California San Francisco
Supporting Metrics or Evidence
Late-stage preclinical
Current Financing Needs
$3 to >$20M
Current Timeline
Preparing IND for clinical trial
Current Investors
Breakout Labs, Founders Fund Science, several angels
IP Status
multiple patents filed worldwide
Recent Milestones
GMP scale-up in preparation for clinical trial; engaging the FDA for Investigator-initiated IND; use of Sleeping Beauty Transposon non-viral vector
Management Team Highlights
Matthew Scholz (Founder and CEO) – Seasoned startup executive; founded and exited Point B Telematics. Eric Herbig, Ph.D., M.B.A. (CSO) – 15+ years of research experience and significant commercialization and management expertise. Zach Hall (Dir. of Operations) – Co-founder and operations director at two previous biomedical startups. Mei Xu, Ph.D. (Dir. of Research) – Molecular biologist with extensive research experience.
J. Zach Hall
Director of Operations 
Matthew Scholz
CEO 

Impatient

Small biotechnology companies are developing half of all future medicines, some of which may not reach patients due to lack of funding from traditional investors.

Although health-related charities received more than $31B in contributions in 2013, many of the charities which support research do not work with for-profit biotech companies. They predominantly fund academic and non-profit institutions which typically conduct early research and discover around 10% of new medicines (for-profit companies discover the remaining 90%).

Impatient is a new kind of health-related charity. We will only fund medical trials with small biotech companies.  

Our scientific advisors will select promising, unfunded, medical treatments. You choose which treatment to support and 100% of your donation is spent on testing.

If the treatment is successful, 100% of the future royalty that Impatient receives from the biotech company will support access to new medicines for people who cannot afford them.  

Capital Structure Preference
Investment Stage Preference
Rosamond Deegan
Acting CEO 

IMS Health Capital, Inc. United States

IMS Health Capital (IMSHC) is a niche life-science focused investment bank which manages financing transactions, and advises on M&A and licensing/partnering transactions.

IMS Health Capital (IMSHC) is a fully owned subsidiary of IMS Health, Inc. (www.imshealth.com) and affiliated with IMS Consulting Group (www.imscg.com).

IMSHC has privileged access to a vast array of IMS Health’s resources and connections and can help prepare a compelling value proposition and put you in touch with the right interested parties.  Our team has extensive life-science industry experience and can provide support at any and all stages of the transaction process.  Unlike most investment banks or business development consultants, IMSHC has immense strategic partnering capabilities and can work with companies on both partnering and financing efforts.  Given our unique positioning and access to a vast array of information and relationships, we see a high volume of opportunities.

IMSHC is a SEC/FINRA licensed broker dealer and a wholly owned subsidiary of IMS Health, Inc.  IMS Health Inc. is publicly traded on the NYSE under the ticker “IMS”, and is the world’s leading information, services and technology company in the Life Sciences sector.  Customers of IMS Health’s data and consulting services include most of the top names in pharmaceutical, medical device and consumer health manufacturers and distributors, providers, payers, government agencies, policymakers, researchers and the financial community (www.imshealth.com).

Website:
www.imscg.com
Service Provider Type
Unique Capabilities
Life-Science focused and IMS Health resources
Mr David Olson
Mr David Olson
LinkedIn logo COO & CCO 
Sam Murphy
Vice President 
Filippo Petralia
Associate