Fred McCoy United States

NeuroTronik Limited is a development-stage, venture-backed medical device company pursuing a unique neuromodulation approach to improve cardac output for patients who come to the hospital with Acute Heart Failure Syndrome. With a seasoned team of engineers, advisors, and investors, NeuroTronik is on-track in project milestone achievement. Though a moderately-sized project, the market potential is exceptional.

NeuroTronik is planning a $20 million Series B preferred stock financing in late 2015. Those proceeds are designed to take the therapy through and into commercial sales in Europe.

Our named investors are Hatteras Venture Partners, Synergy Life Science Partners, Mountain Group Capital, and Lord Baltimore Capital.

The CEO is Fred McCoy. The CTO is Steve Masson.

Year Founded
2012
Main Sector
Indication
Medtech Phase of Development
Technology Overview
Neuromodulation independently engaging both cardiac parasympathetic and sympathetic nerves via electrical stimulation through a temporarily-placed electrode set, controled by a bedside NeuroModulator.
Alliance & Collaborations
Venture-backed.
Supporting Metrics or Evidence
Clearly demonstrated in canines. Early human work is positive.
Current Financing Needs
$20 million Series B late 2015.
Current Timeline
CE Mark and Europe launch 2017.
Current Investors
Hatteras Venture Partners, Synergy Life Science Partners, Mountain Group Capital, Lord Baltimore Capital
IP Status
Licensed and owned. Allowances have started.
Recent Milestones
Series A second tranche earned September 2014
Management Team Highlights
Fred McCoy, CEO: 30+ years experience, former Guidant and Eli Lilly. Steve Masson, CTO: 30+ years experience, former Cordis, Ventritex
NeuroTronik Limited
CEO 

Ashley McMaster United States

The Advanced Medical Technology Association (AdvaMed), is a trade association that leads the effort to advance medical technology in order to achieve healthier lives and healthier economies around the world. AdvaMed represents 80 percent of medical technology firms in the United States and acts as the common voice for companies producing medical devices, diagnostic products and health information systems. AdvaMed members produce nearly 90 percent of the health care technology purchased annually in the United States and more than 40 percent purchased annually around the world. AdvaMed's member companies range from the largest to the smallest medical technology innovators and companies.

AdvaMed 2015 - October 5-7, San Diego - is the leading MedTech Conference in North America, bringing more than 1,000 companies together in a uniquely multifaceted environment for business development, capital formation, innovative technology showcasing, world-class educational opportunities and networking. An event rich in international flavor and featuring a deep, diverse attendee list that includes influential policy-makers, business executives and media, AdvaMed 2015 seeks to advance industry discussion from key perspectives through detailed panel sessions, executive forums and more. It is a “must-attend” event for any MedTech company.

Service Provider Type
Sector Interest
Medtech Phase of Development
Unique Capabilities

AdvaMed 2015 is the place where medical technology leaders meet for business development and investment opportunities.  Emerging medical technology companies connect with top industry decision-makers at AdvaMed 2015 to explore strategic business development and capital formation.

Corporate business development professionals and investors will:

  • Discover the latest medical technologies and innovations during the Innovation Showcase and the MedTech Innovator competition;
  • Gain insights into the key investment issues and industry trends during the Funding Forums and Business Development & Finance Panels.

Innovators and early-stage companies will:

  • Learn how to develop an actionable strategic plan in the Entrepreneurship Boot Camp;
  • Pitch their technologies to investors during the Innovations Showcase and explore strategic business development opportunities through MedTech Partnering.
AdvaMed
Associate Vice President, Membership and Business Development 

Thorsten Melcher United States

Johnson & Johnson (J&J) was founded in 1886 and is based in New Brunswick, NJ, with an Innovation Center in Cambridge, MA. The firm invests in a variety of fields within the life science sector, including medical devices. J&J’s medical device investments are highly varied in both size and structure; the structure may involve milestone payments, or may be an equity investment. J&J is interested in early stage medical device companies located globally.

Johnson & Johnson Innovation
New Ventures 

Jerry Michaud United States

Horizon Technology Finance is a venture lending, investment and financial services management company that was founded in 2003 and is headquartered in Farmington, Ct with additional offices in Walnut Creek, CA and Reston, VA. The firm controls approximately $200 million in assets under management and look to provide senior or subordinate loans to companies in the range of $2 to $20 million dollars, and often syndicates much larger deals. The firm prefers to lead or co-lead investments that they are involved in and looks to be involved in 15 deals in the next 6-9 months. The firm provides capital to companies located throughout the United States and Canada.

Year Founded
2003
Medtech Phase of Development
Capital Structure Preference
Investment Stage Preference
Horizon Technology Finance

Mrs Debra Miller United States

Debra Miller co-founded CureDuchenne in 2003 with her husband, Paul, after their only son was diagnosed with Duchenne. Miller relies on her extensive background in sales and marketing to lead CureDuchenne. 

Her role includes overseeing all operations, research and financial resources as well as serving as the primary liaison to the Board of Directors. She is the decision maker, leader and manager in carrying out the mission of the organization. She also works closely with the Scientific Board of Advisors in designing and implementing the medical research strategic plan.

Miller is a member of the Department of Defense Duchenne Research review board and also a member of the TREAT-NMD international review board, TACT.  Miller has led CureDuchenne’s successful venture philanthropy programs and is the architect of CureDuchenne Ventures LLC, a new, for profit entity created to attract significant research funding to Duchenne research.

Prior to CureDuchenne, Miller had a career in publishing with positions at IDG Communications, Cahners Publishing, Ziff-Davis Publishing and Scholastic Publishing. She also worked in management at PC Magazine and was an independent stock trader.

Miller earned a Bachelor of Arts in Communication Studies from the University of California – Los Angeles. 

Mrs Debra Miller
CureDuchenne
Founder and CEO 

Dr Alton C Morgan United States

PxRadia is applying its HD-mAb technology platform to provide increased therapeutic potency to biosimiliar monoclonal antibodies. These antibodies are directed to validated targets such as Her-2, CD-20 and PD-1/PD-L.  We and our partners will share new IP and rights and differentiation from current products in the marketplace.

Website:
www. pxradia.com
Year Founded
2012
Biotech Subsector
Biotech Phase of Development
Technology Overview
HD-mAb Technology Platform Potentiates Therapeutic Efficacy of Monoclonal Antibodies
Alliance & Collaborations
Pending
Current Financing Needs
$2M
Current Investors
LH Financial, NYC
IP Status
Files
Recent Milestones
Seed Round Financing
Management Team Highlights
Alton C. Morgan, Serial Entrepreneur & world renown Expert in Monoclonal Antibodies
PxRadia Inc.
President and CEO 

Sam Murphy United States

IMS Health Capital (IMSHC) is a niche life-science focused investment bank which manages financing transactions, and advises on M&A and licensing/partnering transactions.

IMS Health Capital (IMSHC) is a fully owned subsidiary of IMS Health, Inc. (www.imshealth.com) and affiliated with IMS Consulting Group (www.imscg.com).

IMSHC has privileged access to a vast array of IMS Health’s resources and connections and can help prepare a compelling value proposition and put you in touch with the right interested parties.  Our team has extensive life-science industry experience and can provide support at any and all stages of the transaction process.  Unlike most investment banks or business development consultants, IMSHC has immense strategic partnering capabilities and can work with companies on both partnering and financing efforts.  Given our unique positioning and access to a vast array of information and relationships, we see a high volume of opportunities.

IMSHC is a SEC/FINRA licensed broker dealer and a wholly owned subsidiary of IMS Health, Inc.  IMS Health Inc. is publicly traded on the NYSE under the ticker “IMS”, and is the world’s leading information, services and technology company in the Life Sciences sector.  Customers of IMS Health’s data and consulting services include most of the top names in pharmaceutical, medical device and consumer health manufacturers and distributors, providers, payers, government agencies, policymakers, researchers and the financial community (www.imshealth.com).

Website:
www.imscg.com
Service Provider Type
Unique Capabilities
Life-Science focused and IMS Health resources
IMS Health Capital, Inc.
Vice President 

John Musser United States

MyeloRx is a northern California based biotechnology company. Our lead compound, MRx102, is a small molecule inhibitor of RNA polymerase II. Molecules related to MRx102 have shown clinical efficacy in AML patients in Europe and China.  MRx102 is covered by issued composition of matter patents in the U.S., E.U., China and Japan.  While AML is the initial indication, MRx102 has also been found active in stringent models of pancreatic and lung cancer. Our collaborators include clinical oncologists from MD Anderson Cancer Center, JHU School of Medicine and City of Hope Medical Center. R&D activities have been funded primarily by a $2M NCI SBIR contract. Our strong scientific and management team is lead by Dr. John Musser; it has brought multiple products to market. We are seeking funding to complete an IND which is projected to take less than a year based on the extensive studies completed to date (manufacturing, formulation, toxicology/ PK in rats and dogs etc.)  and a Phase 1 clinical trial in AML patients.

 

Website:
www.myelorx.com
Year Founded
2007
Biotech Subsector
Technology Overview
The lead compound is termed MRx102. It is a prodrug of a purified natural product triptolide that has shown clinical activity in patients with acute myeloid leukemia (AML). Intellectual property MRx102 is covered by issued matter patents in the U.S., E.U., Japan and China. Molecular target The molecular target of the natural product, triptolide, is XPB, a subunit of the transcription factor TFIIH. Binding of XPB by triptolide leads inhibition of transcriptional activation resulting in the blockade of a number of signaling pathways that drive cancer cell proliferation. Safety Triptolide and earlier prodrugs of triptolide have shown toxicity in a variety of clinical studies. We therefore set out to design and develop a safe prodrug, viz. MRx102, using the learning from these earlier studies. In a direct comparative toxicology study performed in rats MRx102 was at least 20 times safer than triptolide. This was due to a favorable pharmacokinetic profile seen both in rats and dogs. Pilot toxicology/PK studies have been completed in rats and dogs; NOAELs have been determined in both species. Thought Leader Studies with MRx102 In collaboration with Dr. Michael Andreeff of the MD Anderson Cancer Center we demonstrated that MRx102 was extremely potent in killing human blast cell and stem cell populations from AML patients. The activity against the stem cell populations may indicate an activity in preventing relapse in these patients. MRx102 was likewise effective in a variety of in vivo xenograft models of AML. Dr. James Eshleman and his colleagues from the JHU School of Medicine have demonstrated the activity of MRx102 in killing pancreatic cancer cells having a variety of genetic abnormalities. Dr. Dan Raz of the City of Hope Medical Center has shown MRx102 effective in models of non-small cell lung cancer and identified a potential biomarker for susceptible cells. Current status MyeloRx has completed a $2M NCI Fast Track SBIR contract that enabled many preclinical activities required for an IND filing. Major remaining activities include the GMP manufacture of drug substance, performance of GLP toxicology in rats and dogs and then completion of the clinical plan for Phase 1 studies in AML and solid tumors. These could be completed to allow IND filing in less than a year.
Alliance & Collaborations
Option agreement for China territories
Current Financing Needs
$5-7M for IND filing/Phase 1 trial
Current Timeline
IND completion in less than one year
IP Status
Issued matter patents worldwide
Recent Milestones
Completion of tox/PK studies in rats/dogs
MyeloRx
CEO 

Barbara Nelsen United States

Sofia Angel Group is a group of angel investors based in Minneapolis, Minnesota. The group solely focuses on investing in women-led businesses where women are the founders, or women are on the senior management team. Sofia Angel Group does not have a specific timeframe to make an investment, however would make an allocation by the end of 2013 if a compelling opportunity is identified. The group typically invests around $100,000 per company, however has the ability to invest up to $3 million through co-investments from the group’s members.

Sofia Angel Fund

Carey Ng United States

Mesa Verde Venture Partners is a Venture Capital company founded in 2006. The firm is currently making investments out of its 2nd fund that had its first close in 2013. The firm makes primarily equity investment into seed and early stage rounds ranging from $500,000 to $1 million initially and up to $1.5 million over the lifetime of the investment. The firm is focused on companies located in the Southwestern United States although they are open to review companies from throughout the US. The firm could make as many as 3 new investments over the next 6-9 months.

Year Founded
2006
Investor Type
Biotech Phase of Development
Medtech Phase of Development
Capital Structure Preference
Investment Stage Preference
Mesa Verde Venture Partners
Managing Director