Alistair Duncan

viDA is a preclinical biotechnology company pursuing the development of first-in-class drugs for the treatment of several inflammatory and age-related conditions of the skin, respiratory, musculoskeletal, cardiovascular, and neurological systems.Our platform is based on recently identified, specifically extracellular, pathological roles of a family of serine proteases called Granzymes. 

Currently, our focus is specifically on extracellular Granzyme B (GzmB) and its role in a range of disease states involving inflammation and tissue damage. GzmB actively participates in the degradation of key components of the body’s extracellular matrix, which acts as a scaffold for cell binding and provides essential structural integrity for proper function of tissues and organs.

Based on this new mechanism of action, these molecules have shown positive therapeutic outcomes in a number of disease-specific models. viDA has been reviewing MS and the orphan indication of Discoid Lupus specifically.

Our lead compound is in preclinical development and is intended to be a topical treatment for Discoid Lupus. The lead candidate exhibits a high degree of specificity and selectivity for extracellular GzmB. The compound has attractive drug-like properties for topical application and is being assessed for other possible routes of administration amenable to treatment of other diseases.

The Company has developed a library of additional proprietary first-in-class small molecule inhibitors to GzmB. These innovative molecules will have specific properties amenable to treatment of diseases requiring different routes of administration. 

Studies using inhibitors and knockout approaches have demonstrated that GzmB inhibition does not suppress immunity.

 

Biotech Subsector
Biotech Phase of Development
Technology Overview
viDA's platform is based on recently identified, specifically extracellular, pathological roles of a family of serine proteases called Granzymes. 

Currently, our focus is specifically on extracellular Granzyme B (GzmB) and its role in a range of disease states involving inflammation and tissue damage. GzmB actively participates in the degradation of key components of the body’s extracellular matrix, which acts as a scaffold for cell binding and provides essential structural integrity for proper function of tissues and organs. viDA is developing a library of GzmB inhibitors containing both biologics and small molecules focusing on this new mechanism of action.
Alliance & Collaborations
Collaborators from University of British Columbia, Rick Hansen Institute, Institute for Heart + Lung Health, Providence Health Care Research Institute, and Genome British Columbia work with viDA to advance our technology platform and research programs.
Current Financing Needs
viDA has raised $6M equity to date from VC and angel investors 11.4M common shares outstanding (12.6M fully diluted)
Current Timeline
viDA will complete preclinical work to file an IND on our lead program in wound healing in Q4 2015 in preparation for a Phase 1 clinical trial in 2016
Current Investors
BDC Capital
IP Status
viDA's IP covers novel inhibitors, age-related degenerative processes, wound healing, cardiovascular, other inflammatory conditions and use of Granzyme levels as a biomarker.
Recent Milestones
Advanced first-in-class GzmB inhibitor program in tissue repair • Pre-IND studies (efficacy and lead optimization) to complete in 2015 • IND enabling studies (GLP pharm/tox) to initiate in 2015 Expanded library of proprietary inhibitors • Second generation of small molecules and additional biologics in development
viDA Therapeutics
President & CEO 

Mr Blair Duncan United States

Regeneration Through Innovation

Celling Biosciences is dedicated to researching and developing the future of healing through regenerative medicine and the clinical use of autologous regenerative cells to facilitate the body’s capacity to heal itself. Through our patented Celling therapies and our Institutes of Regenerative Medicine, Celling Biosciences is moving the science of healing forward and redefining the global medical landscape.

Year Founded
2006
Biotech Subsector
Biotech Phase of Development
Medtech Phase of Development
Technology Overview
Regeneration Through Innovation

Celling Biosciences is dedicated to researching and developing the future of healing through regenerative medicine and the clinical use of autologous regenerative cells to facilitate the body’s capacity to heal itself. Through our patented Celling therapies and our Institutes of Regenerative Medicine, Celling Biosciences is moving the science of healing forward and redefining the global medical landscape.

Current Financing Needs

$3-10 million growth capital with opportunity for partial founder buy-out.

Management Team Highlights
Kevin Dunworth

Founder / CEO

Kevin Dunworth, Founder of Celling Biosciences, has spent more than 26 years in the orthopedic industry and brings a wealth of expertise in all aspects of the business. Dunworth has run medical companies in the Middle East, Eastern and Western Europe, and the United States.

He excelled in various executive positions before founding VCD Medical, in Austin, Texas.
For the past eight years, Dunworth has successfully built a world-class distribution business, which provides a variety of orthopedic and biologic products.

Dunworth's leadership roles within the orthopedic industry have included, Director of Emerging Markets and Director of European Sales for Smith & Nephew; Director of International Sales, Vice President of Worldwide Sales and Vice President for FlouroScan International and Vice President of Sales for TransLeasing and Vice President for TransLeasing GE.


Steve Melchiode

President
Steve Melchiode has extensive experience guiding businesses from start-up to profitability. After earning an undergraduate marketing degree followed by a law degree, Melchiode joined a start-up technology firm in Silicon Valley as the West Coast business development director. Melchiode's ability to build and lead successful companies, combined with his experience in medical device sales, provides him with the vision and expertise to lead the Celling Biosciences team. He brings a wide range of experience in sales, business development, marketing, finance, legal and operations management.

Melchiode began his medical device career as a sales representative with VCD Medical, learning the spinal implant industry selling Depuy Spine. After two years spent growing several new territories, Melchiode established himself in a leadership role as sales manager and by running operations for the State of Texas. For the past two years, he has worked with Kevin Dunworth to take the Celling Biosciences model from concept to market, working on business, product and partnership development as well as marketing and operations.

Mr Blair Duncan
Celling Biosciences
LinkedIn logo Chief Financial Officer 
BIO

Blair Duncan, Chief Financial Officer, Celling Biosciences

 

Mr. Duncan has over 20 years experience in venture-backed growth companies, as well as Fortune 500 and service firms. Before joining Celling Biosciences, Mr. Duncan was Chief Financial Officer at Emergent Technologies, an early stage life sciences commercialization operator and venture capital firm.  Previously, Mr. Duncan was Chief Financial Officer and Controller at SiteStuff, a leading provider of online procurement services for the commercial real estate industry.  Prior to SiteStuff, Mr. Duncan was Chief Financial Officer for Trillion, a facilities-based provider of wireless broadband telecommunications services to K-12 school districts.  Mr. Duncan also served as Vice President and Controller for ClearSource, a facilities-based provider of broadband telecommunications services.  Mr. Duncan held positions at PricewaterhouseCoopers as Manager of Entrepreneurial Advisory Services, where he launched a new division providing fundraising and business planning consulting services to high-tech companies in Texas, as well as Manager in the Business Assurance practice, where he participated in numerous public offerings and private company audits.  Mr. Duncan started his career with Aetna as a manager of property and casualty underwriting and business development. 

 

Mr. Duncan is a CPA and holds a MBA from the University of Texas at Austin.  He has a BA in Economics and Psychology from Duke University. Mr. Duncan enjoys travel, music, tennis and golf.  He is Career Services Chair of the Financial Executives International – Austin Chapter, as well as Treasurer of the Maya Exploration Center.  He is married with three children and resides in Austin, Texas.

Clayton Duncan

Accele Biopharma
CEO 

Mike Dybbs

New Leaf Venture Partners is a venture capital company formed in 25 with offices in New York and San Mateo California. The firm currently manages two funds with its most recent fund having closed at $45 million in 27. The firm is looking to make equity investments ranging from $1-$25 million over the lifetime of the investment. The firm looks for companies primarily in the United States and some select opportunities in Europe. The firm plans to make between 1-5 investments over the next year.
New Leaf Venture Partners
Principal 

Imran Eba

Action Potential Venture Capital is an evergreen strategic venture capital fund of GlaxoSmithKline which closed at $1 million in 213 and is managed by a small dedicated team based in Cambridge Massachusetts and Palo Alto California. The fund focuses on investments in companies developing pioneering bioelectronic medicines (essentially neuromodulation devices) and related enabling technologies. The initial investments are typically ranging from $5-$7 million in Series A and the fund will also consider follow-on investments. Action Potential Venture Capital looks for investment opportunities globally.
Website:
www.gsk.com
Sector Interest
Biotech Phase of Development
Medtech Phase of Development
Capital Structure Preference
Investment Stage Preference
Action Potential Venture Capital
Partner 

Laura Eggink

Website:
www.susavion.com
Susavion Biosciences Inc.
President 

Mr Glenn Engelmann United States

McDermott Will & Emery is a premier international law firm with a unique focus in representing life sciences companies and investors in a wide variety of transactional, intellectual property and regulatory matters.  Through our Life Sciences Entrepreneurs Acceleration Program ("LEAP") we provide early stage medical device, pharmaceutical, biotechnology and diagnostic companies access to sophisticated legal services.  Learn more here: http://www.mwe.com/leap/

Website:
www.mwe.com
Service Provider Type
Medtech Phase of Development
Unique Capabilities
Life Sciences Entrepreneurs Acceleration Program (LEAP)

McDermott Will & Emery is dedicated to investing in innovation and serving the early stage life sciences community that creates new and revolutionary products and services. We understand that sophisticated legal services are necessary to help these groundbreaking individuals and organizations succeed. McDermott is proud to have created the Life Sciences Entrepreneurs Acceleration Program (LEAP) to help qualifying entrepreneurs and young companies avoid costly mistakes and chart their courses to success by providing support and affordable access to strategic legal advice. We provide these organizations with high quality legal services during the earliest stages of corporate life through engagement incentives in the form of deferred fees, discounts, fixed-fee arrangements and/or awards.

We understand that early stage life sciences clients need legal advice in such complex areas as corporate formation, financing, intellectual property, licensing and collaborations, and employee benefits. Our Life Sciences Industry Group has a deep bench of lawyers that are highly regarded in these specific practices. Our corporate lawyers have demonstrated success in advising life sciences companies on the full range of transactional legal needs, including licensing and partnering, mergers and acquisitions, venture capital, public offerings and royalty stream financing. Our intellectual property lawyers are renowned for protecting the IP rights of our clients both in and out of court. Finally, McDermott is a pioneer in the field of employee benefits and has been advising life sciences companies on various compensation strategies to both secure and maintain leadership.

McDermott Will & Emery
Vice Chair, Life Sciences McDermott Will & Emery 

Robin Engstrom

TriNet
Regional Sales Consultant, Life Sciences and Biotech 

Lesley Esford Canada

The National Research Council- Industrial Research Assistance Program (NRC-IRAP) is a Canadian federal government program that offers financial and advisory services to accelerate the growth of businesses through innovation and technology. Regarded worldwide as one of the most successful programs of its kind, NRC-IRAP is a vital component of Canada’s innovation system

 

National Research Council of Canada
Strategic Business Advisor