Dr Femida Gwadry-Sridhar Canada

Pulse Infoframe Inc strives to improve workflow using computer-assisted capture of patient data for specialists – our cloud based software enables better local and global sharing of the data for those who need it to make decisions – our end-user driven tools analyze the data to advance knowledge and thus patient care. Data can be directly entered into our system, and because we sit on top of any EMR system we access additional data that is not otherwise easily accessible. Once accessed, the data is de-identified, aggregated and mined producing meaningful information for our end-users. 

-----------------------

We have applied our solution in various clinical verticals including speciality clinics (Melanoma, Oncology, Neonatology, etc), Imaging and PACS systems (with INFINITT PACS, ClearCanvas, etc) and clinical trials (tracking prostate cancer, Pharmacovigilance, economics, etc). Modules are versatile and can be templated to be used in a variety of systems for achieving the best workflow possible.

Year Founded
2011
Main Sector
Medtech Phase of Development
Technology Overview
Our flagship product is a cloud-based clinical and informatics solution that acts either as a stand-alone system aggregator or is interoperable with existing EMRs. Our solution is a database-driven informatics tools can be used for creating, maintaining, organizing and modeling clinical and outcomes data. Our sophisticated analytics engine can access data so that end-users can dynamically conduct online analysis and reporting. All clinical, imaging and administrative data is aggregated from heterogeneous data sources and is organized for effortless analytics. Data is securely stored within our platform with full reporting or auditing abilities.
Dr Femida Gwadry-Sridhar
Pulse Infoframe Inc.
LinkedIn logo Co-Founder & CEO 
BIO

Dr. Femida Gwadry-Sridhar is the Co-Founder and CEO of Pulse Infoframe Inc. She is a pharmacist, epidemiologist and methodologist with over 25 years of experience in clinical trials, disease registries, knowledge translation, health analytics and clinical disease outcomes.

Dr Carl Hansen Canada

AbCellera has developed a next generation technology for the analysis and screening of naturally derived immune repertoires. This platform uses high-throughput single cell analysis to enable the discovery of naturally derived monoclonal antibodies with unmatched speed, efficiency, and assay flexibility. By eliminating the need to culture cells this approach may be applied to antibody discovery from non-traditional host species, including rabbits and llamas, and achieves industry-leading capabilities in isolating antibodies from patient samples, with applications in infectious disease and autoimmunity.

AbCellera is engaged in antibody discovery projects with early partners, including biotech and pharma companies, and is also initiating internal programs aimed at using immune profiling for target identification and lead molecule discovery.

We are looking for Series A financing from strategic investors, as well as new partnerships with antibody drug development companies.

 

Dr Carl Hansen
AbCellera
CEO & President 

Mr Michael Lincoln Canada

CDRD Ventures Inc. (CVI) is the commercialization vehicle of the Centre for Drug Research and Development (CDRD), Canada's national drug development and commercialization center that was founded in 2007 and is based in Vancouver, Canada. CVI seeks to advance promising drug development projects from CDRD using internal funds and through partnerships with international pharmaceutical companies, venture capital firms, biotech companies, and other funding agencies. CVI also seeks to in-license technologies from industry or non-CDRD affiliated research institutions. The firm considers both small molecule and biologic innovative technologies in virtually any therapeutic area.

CDRD Ventures
Chief Financial and Business Officer 

Dr Pradip Maiti Canada

Immunimed Inc is a clinical-stage Biopharmaceutical company developing innovative egg-derived, oral potclonal antibody therapy to treat gastro-enteric infections/diseases. Our lead product IMM-001 targets super bug, Clostridium difficile, leading cause of hospital-acquired infections.

Currently is Phase II ready with remarkable clinical response in Proof on Concept multi-center clinical studies.  Phase II clinical study is planned for Q2 2015.

Year Founded
2013
Biotech Subsector
Biotech Phase of Development
Current Financing Needs

$5-6M to complete clinical development.

Current Timeline

Q1-Q2-2015

IP Status

Four patents issued and one pending

Immunimed Inc.
President 

Ian McBeath Canada

Naegis, based in Vancouver, British Columbia, is developing novel, small-molecule leukotirene synthesis inhibitors (LTSIs) for serious inflammatory conditions.  The Company is currently focused on two proprietary programs: 

topical and oral therapy for Uveitis, a condition that is responsible for 10% of legal blindness in the US and for which there are limited therapeutic options. 

o oral therapy for Chronic Obstructive Pulmonary Disease (COPD),  a serious lung disease with increasing rates of mortality.

Naegis has developed a large library of LTSIs that are potent inhibitors of either 5-LO or LTA4H.  The Company is currently identifying a lead compound for selection for futher development for ocular disease, in particular Uveitis.

The Company is also advancing a series of compounds that are novel structures and highly selective and potent inhibitors of LTA4H, which are expected to be developed as new therpaies for COPD

Naegis is seeking pharmaceutical partners and capital investment to advance more rapidly their novel programs.

Year Founded
2010
Biotech Subsector
Biotech Phase of Development
Technology Overview
Leukotrienes are key inflammatory mediators implicated in many diseases. There is growing evidence of their central role in Uveitis. 5-LO inhibitors have been shown to reduce the clinical signs of uveitis in animal models. Naegis is developing potent 5-LO inhibitors that are both topically and orally active, with unique structures that are not expected to have the limitations of earlier 5-LO inhibitors. In COPD recent evidence has demonstrated the critical role for LTA4H in the progression and persistence of the disease. However it has recently been shown that LTA4H has a dual role and functions as both a pro and anti-inflammatory. Thus it is necessary to identify compounds that are active only against the pro-inflammatory function of the enzyme, whilst sparing its anti-inflammatory effects. Naegis is developing highly specific inhibitors of LTA4H that inhibit only the anti-inflammatory activity of LTA4H.
Alliance & Collaborations
In discussion
Current Financing Needs
$500,000 - $1,000,000
Current Timeline
Lead
Current Investors
Private.
IP Status
Proprietary compounds
Management Team Highlights
CEO - Dr. David Burgoyne an experienced medicinal chemist who has developed compounds that are in current human clinical trials. Also on the Board are Dr. Philip Davies, formerly Executive Director of Research and Area Head of Immunology at Merck, New Jersey. Also Dr Julia Levy, founder of QLT and developer of the first effective therapy for macular degeneration.
Ian McBeath
Naegis Pharmaceuticals Inc.
Corporate Development 

Dr Aliasgar Morbi Canada

GaitTronics has developed a robotic patient handling system called SoloWalk. SoloWalk provides effortless mobility for frail patients which would otherwise require two or more caregivers to assist them and put the patients at risk of falling. With SoloWalk's intelligent patient driven mobile system, a single caregiver can mobilize a patient. Additionally, an automatic fall protection system supports the patient automatically if a balance loss is detected, significantly reducing the risk of injury for patients and staff.

Currently, hospitals are only providing adequate mobility for 30% of their patients. With SoloWallk, these institutions can expect to significantly increase this proportion and reduce complications associated with immobility, including: functional decline, bed sores, increased delirium and increased length-of-stay. With the potential of reducing length-of-stay by two days, there is a significant ROI for using SoloWalk in an acute care setting.

Watch a demo of SoloWalk at http://youtu.be/tIcfEsnQ4uY .

Website:
GaitTronics.com
Year Founded
2012
Main Sector
Indication
Medtech Phase of Development
Technology Overview
SoloWalk is a patient handling robot that helps frail patients get up and walk. Early mobility can significantly reduce complications associated with immobility and can reduce length-of-stay by two days.
Current Financing Needs
We are currently seeking to raise a $1.1M seed round.
Current Timeline
Product launch is targeted for early 2016.
IP Status
Pending
Recent Milestones
Initiated first clinical trial at the Ottawa Children's Treatment Centre with adolescent cerebral palsy patients.
Dr Aliasgar Morbi
Gait Tronics
LinkedIn logo ‎Chief Technology Officer and Co-founder 

Michael Parr Canada

Sitka Biopharma is a preclinical stage company focused on developing a breakthrough nanoparticle platform technology designed to increase absorption of drugs in difficult-to-penetrate tissues. Initially targeting oncology indications, we are developing our lead candidate to address the absorption challenge of intravesical chemotherapy for bladder cancer, and later intraperitoneal delivery for ovarian cancer.

We have demonstrated preclinical proof-of-concept for our lead candidate using in vivo and ex vivo models for bladder cancer.
Our goal is to complete our IND in 2015 and begin a Phase 1/2a Proof-of-Concept clinical trial in nonmuscle-invasive bladder cancer in 2016.

Partnership Opportunities for Platform Technology:

Our nanoparticle platform technology offers unique benefits over other nano-delivery systems and has the potential to be combined with a variety of different drugs to improve absorption for therapeutic uses in both humans and animals.

Benefits of Sitka's HPG nanoparticle platform include:

  • unimolecular structure
  • small size (8-10 nm)
  • tailored for a high degree of localized drug bioavailability in large surface applications
  • potential utility with a wide variety of drugs and indications

We welcome opportunities to collaborate with biopharmaceutical companies that wish to take advantage of our platform technology.

Year Founded
2013
Biotech Phase of Development
Technology Overview
Our nanoparticle platform technology offers unique benefits over other nano-delivery systems and has the potential to be combined with a variety of different drugs to improve absorption for therapeutic uses in both humans and animals. Benefits of Sitka's HPG nanoparticle platform include: unimolecular structure; small size (8-10 nm) and low viscosity; tailored for a high degree of localized drug bioavailability in large surface applications; potential utility with a wide variety of drugs and indications
Current Financing Needs
Seed private investment of $500,000; can be leveraged 2:1 up to $1.5M via partnership with CVI founded Accel-Rx (www.accel-rx.com)
Current Timeline
IND/Entry into clinic in early 2016
Current Investors
CDRD Ventures Inc (www.cdrdventures.com)
Sitka Biopharma Inc.
President & Chief Scientific Officer 

Mohammed Qadir Canada

Fusion Genomics Corp (FG) is a molecular diagnostic test  development company that is introducing diagnostic kits with companion analysis software that offer superior clinical information, faster turn-around-times and ease of use for hospitals and clinical laboratories. Fusion is the first of two companies in the world to bring a validated Next Generation Sequencing (NGS) diagnostic test complete with highly secure cloud based analytical service for childhood cancers (ChildSeq-RNA SRCT) into the clinic. This test was validated in the renowned medical testing facility at the Texas Children Hospital, Baylor College of Medicine.

FG is completing development of kits for facilitating absolute diagnosis of pediatric and adult blood cancers. In addition, FG has partnered with the Royal Tropical Institute (Dutch: Koninklijk Instituut voor de Tropen; KIT) a World Health Organization reference diagnostic laboratory for infectious diseases to design the next generation of assays for the detection of infectious diseases including drug-resistant forms of tuberculosis, influenza, hepatitis and hemorrhagic fevers including Ebola.

Year Founded
2013
Biotech Subsector
Medtech Subsector
Biotech Phase of Development
Medtech Phase of Development
Technology Overview

Fusion Genomics Corporation (FG) develops molecular diagnostic tests that utilize next-generation sequencing (NGS) technologies. All of FG’s tests can be used with any of the widely adopted NGS instruments on the market. Data is analyzed using FGF’s secure FusionCloud, providing diagnosis –enabling DNA sequence information to the clinician.

Most NGS based diagnostic efforts can be divided into two categories: 1) whole genome sequencing (WGS), where the entire DNA of an individual (or a pathogen) is sequenced, and 2) target-capture sequencing (TCS), where only diseased portions of DNA are sequenced. TCS produces 1000 times less data than WGS. The expensive computational resources required for analysis of WGS data prevents it from being adopted for routine clinical use. Therefore, TCS is more suitable and appealing in frontline diagnostic environments.

TCS uses either PCR or “DNA baits” as the underlying technology to “capture” disease-specific regions of the genome. PCR-based methods suffer from limitations described earlier. FG uses proprietary Quantum ProbesTM, an enhanced form of DNA baits, in all its tests. Quantum ProbesTM allow for nearly limitless expansion of genetic targets and rapid development of new tests as well as patentable techniques that are beyond the capacity of PCR. The superior advantage of Quantum ProbeTM, coupled with FusionCloud analysis and reporting, will drive the successful adoption of the tests. 

Alliance & Collaborations
Texas Children Hospital, Baylor College of Medicine (Houston, USA), British Columbia Centre for Disease Control (Vancouver, Canada), Royal Tropical Institute / Koninklijk Instituut voor de Tropen (Amsterdam, Netherlands)
Supporting Metrics or Evidence

The Fusion Genomics team published a very well received peer-reviewed publication which demonstrated that their technology was more sensitive, accurate, rapid and comprehensive than current industry standards such as PCR and FISH.  This study can be found at here.

Current Financing Needs

 $0.5-1M to complete seed round

Current Investors

Founders, board members, family and friends.

IP Status

Patent applications are pending.

Management Team Highlights

Fusion Genomics Corporation’s team has established expertise in next-generation sequencing, diagnostic test and software development, and information technology.

Mohammed Qadir, PhD., Chief Executive Officer and Chief Scientific Officer has over 17 years of research experience; the last 10 were at the British Columbia Cancer Agency. As part of his early training, he worked with world-renowned experts in genomics and drug development and is the co-inventor of the ChildSeq assay and ChildDecode.

Greg Stazyk, Chief Technical Officer has over 20 years of experience in senior positions in the IT industry. Mr. Stazyk was the IT lead for one of Canada’s largest bioinformatics computing platform at the BC Cancer Agency’s Genome Sciences Centre (GSC). Mr. Stazyk was the senior manager at PMC-Sierra Inc. responsible for its global computer systems operation.

Brian Kwok, VP of Product Development has close to 10 years of experience in molecular biology and genomic technologies including leading edge next-generation sequencing. Mr. Kwok has worked in combinatorial drug screening and led the development of the ChildSeq assay.

Dr. Poul Sorensen MD, PhD: Board member and clinical expert. Dr. Sorensen is a world-renowned pediatric pathologist and is the Johal Chair in Childhood Cancer Research at the University of British Columbia, as well as a professor in the Department of Pathology and a Senior Scientist at the BC Cancer Research Agency (Vancouver, Canada). Dr. Sorensen is also the Chair of the Translational Research committee of the Children’s Oncology Group.

Fusion Genomics Corporation
Chief Scientific Officer 

Euan Ramsay Canada

Precision NanoSystems Inc. (“PNI”) has developed proprietary technology (NanoAssemblr) and companion Reagent Kits (SUB9KITS) that enable the simple manufacture of novel nanoparticles that are used to delivery genetic and small molecule medicines (nanomedicines). Nanomedicines are the "FedEx" of the health-care industry and are used for cell-specific delivery of research tools, diagnostic imaging agents and drugs to study, diagnose and treat disease. PNI's products are commercialized and in high demand from many of leading RNA and small molecule therapeutic biotechnology and pharmaceutical companies.  http://www.precisionnanosystems.com/products/

Year Founded
2010
Biotech Phase of Development
Current Financing Needs
PNI is currently raising Series A financing.
Recent Milestones
PNI launched its flagship NanoAssemblr Benchtop and SUB9KIT products in H2 2013. Since that time, PNI has seen significant latent demand for its products and is rapid expanding product manufacturing to satisfy market need. Additionally, PNI has achieved important technical milestones in it's large-scale nanomedicine platform and SUB9KIT products.
Management Team Highlights
PNI’s management, directors & advisors have collectively contributed to over 100 patents and 500 papers, started over 20 biotech companies, raised over $1B in financing/deals and have brought 4 drugs to market. PNI’s CEO, Dr. James Taylor has over 10 years of experience in commercializing biotech and has lead PNI since invention. PNI’s COO, Dr. Euan Ramsay, has 13 years commercializing biotech, has secured over $40M in leveraged financing, and has developed nanomedicines to clinical trials.
Precision NanoSystems
COO 

Mr Sanj Singh Canada

“AdeTherapeutics’ approach has potential to become standard of care,” says Dr. Greenberg, Vice Chair Obs & Gyn at Brigham and Women’s Hospital and Associate Professor at Harvard Medical School.

Our platform technology which KOL’s have pointed out as a game changer in the area of preventing post operative fibrosis, is poised to create significant value.  The pipeline contains a phase II drug for prevention of post operative fibrosis following pelvic and abdominal surgeries, med devices (collaboration with DSM Biomedical) for spinal surgery and additional opportunities in orthopedics.  

The Company has built a world class team, utilized a capital efficient, highly targeted and focused approach and brought on the necessary strategic partners to bring first-in-class products to the market and establish standard of care for millions of surgeries worldwide.Key value propositions:

•             useful in more procedures than current medical devices

•             significant higher efficacy vs market comparators

•             attractive safety profile & accelerated regulatory pathway

Key Milestones achieved:

  • Phase II trial started
  • Key markets patents issued: USA, EU, Japan
  • Efficacy shown in different tissues areas
  • Two peer reviewed publications in 2014

 

Biotech Subsector
Biotech Phase of Development
Medtech Phase of Development
Technology Overview
. Key publications in 2014 by leading authors in the space supports our novel cellular and molecular approach. Evitar is used at the time of surgery to correct the imbalance in the system brought on by surgical injury which triggers the cascading activation of many pro-inflammatory pathways (including TGF-Beta) that promote adhesion or fibrosis development.
Alliance & Collaborations
DSM Biomedical, Evonik Industries (Mftring) and exploring others
Supporting Metrics or Evidence
publications, preclinical data and POC reading out in early 2015
Current Financing Needs
$5-$6 million
Current Timeline
POC early 2015 for lead indication, moving second indication into the clinic by end of 2015
Current Investors
privately financed by management and board
IP Status
patents issues in major markets
Recent Milestones
phase II trial initated, USA patents issued, two key publications in 2014 in peer reviewed journal
Management Team Highlights
Significant experience in busines devleopment, marketing, clinical, regulatory and buisness development in the hospital space and med devices and therapeutics
AdeTherapeutics Inc
LinkedIn logo President - CEO