Mr Sanj Singh Canada

“AdeTherapeutics’ approach has potential to become standard of care,” says Dr. Greenberg, Vice Chair Obs & Gyn at Brigham and Women’s Hospital and Associate Professor at Harvard Medical School.

Our platform technology which KOL’s have pointed out as a game changer in the area of preventing post operative fibrosis, is poised to create significant value.  The pipeline contains a phase II drug for prevention of post operative fibrosis following pelvic and abdominal surgeries, med devices (collaboration with DSM Biomedical) for spinal surgery and additional opportunities in orthopedics.  

The Company has built a world class team, utilized a capital efficient, highly targeted and focused approach and brought on the necessary strategic partners to bring first-in-class products to the market and establish standard of care for millions of surgeries worldwide.Key value propositions:

•             useful in more procedures than current medical devices

•             significant higher efficacy vs market comparators

•             attractive safety profile & accelerated regulatory pathway

Key Milestones achieved:

  • Phase II trial started
  • Key markets patents issued: USA, EU, Japan
  • Efficacy shown in different tissues areas
  • Two peer reviewed publications in 2014

 

Biotech Subsector
Biotech Phase of Development
Medtech Phase of Development
Technology Overview
. Key publications in 2014 by leading authors in the space supports our novel cellular and molecular approach. Evitar is used at the time of surgery to correct the imbalance in the system brought on by surgical injury which triggers the cascading activation of many pro-inflammatory pathways (including TGF-Beta) that promote adhesion or fibrosis development.
Alliance & Collaborations
DSM Biomedical, Evonik Industries (Mftring) and exploring others
Supporting Metrics or Evidence
publications, preclinical data and POC reading out in early 2015
Current Financing Needs
$5-$6 million
Current Timeline
POC early 2015 for lead indication, moving second indication into the clinic by end of 2015
Current Investors
privately financed by management and board
IP Status
patents issues in major markets
Recent Milestones
phase II trial initated, USA patents issued, two key publications in 2014 in peer reviewed journal
Management Team Highlights
Significant experience in busines devleopment, marketing, clinical, regulatory and buisness development in the hospital space and med devices and therapeutics
AdeTherapeutics Inc
LinkedIn logo President - CEO 

Dr Patrick Sislian United States

Deton is developing a novel non-invasive simple-to-use sample collection device for tuberculosis (TB) patients who are unable to provide a sample.

Proper diagnosis is essential to effectively treat the more than 9million new cases of TB every year. Typically, a sputum sample is collected to run the diagnostic test. However, in 22% of adults and in all children patients, sputum is impossible to collect. These patients have to rely on inadequate alternative collection methods that are invasive, high-cost, and resource-intensive. With our device, patients can now provide a sample even in low-resource setting and find out their TB status. Deton will enable 26M samples to be tested every year.

After promising clinical data, Deton is now raising $1.6M to build an ISO 13485 disposable product and to obtain pivotal clinical validation. Discussions with multiple potential diagnostic partners and first feedback from experts at World Health Organization show significant interest in adopting the device once effective validation has been completed. 

Year Founded
2011
Main Sector
Medtech Phase of Development
Technology Overview
Cough collection to diagnose respiratory infections
Alliance & Collaborations
Confidential
Supporting Metrics or Evidence
human clinical data supporting the diagnostic
Current Financing Needs
Deton is raising a $1.6 million seed round to support 15 months of operations.
Current Timeline
Milestones: (1) develop an ISO-13485 final design disposable device (t+10 months) and (2) obtain pivotal clinical data in 50 patients (t+15 months). Deton’s third major milestone during the seed stage is to obtain Series A financing.
Current Investors
non-dilutive government grants
IP Status
The Cough Collector is protected by 2 Patent Cooperation Treaty applications fully owned by Deton: PCT/US2011/042854 –“System for airborne bacterial sample collection and analysis” and PCT/US2014/024682 – “System for breath sample collection and analysis.”
Recent Milestones
With non-dilutive funding from government grants, the Cough Collector has been tested in a study on a limited number of patients at a high prevalence site with very encouraging results.
Management Team Highlights
Deton’s team brings together more than 20 years of experience in each of engineering, medicine, and commercial operations. Our team has successfully taken a product from idea to human clinical data. Founders: Patrick Sislian, (CEO, PhD Chemical Engineering UCLA, Member of UCLA VC Fund), Stephen Chapman (VP of R&D, PhD Chemical Engineering Caltech), and Ramzi Nasr (VP of Clinical, PhD Bioinformatics UCI). Part-time: Nico Arnold (previous EVP of commercial ops at Cepheid, previous SVP at Siemens), Dr. Antonio Catanzaro (clinical expert on TB, Professor of Medicine at UCSD), and Katrina Fiedler (previous Director of Regulatory affairs at Alere).
Deton Corp.
LinkedIn logo CEO 
BIO

Patrick Sislian is co-founder and CEO of Deton. He has successful track record in product development. He has secured more than $1.2M in government grants from the NSF, NIH, DoD. He holds a Ph.D. in chemical engineering from UCLA. He serves on the Life Science Investment Committee of the UCLA Venture Capital Fund.

John Slump United States

Headquartered in the greater Iowa City area, Corvida Medical innovates intelligent technologies that are designed to represent the next generation of safe handling of hazardous drugs and excellence in design.  We address the problems inherent in current methods and develop smarter, simpler solutions to improve safety, productivity and quality for providers and patients. Our first technology, a novel new Closed System Transfer Device – the Halo™ — will be available in 2015.

Indication
Biotech Phase of Development
Medtech Phase of Development
Technology Overview

Corvida Medical is an emerging device company optimizing the safe handling of hazardous drugs, such as chemotherapeutics used to treat cancer patients. Millions of healthcare providers are at risk of exposure to hazardous drugs each year, resulting in adverse events such as cancers, reproductive toxicity, genetic mutations, etc. The company has developed anInnovative Device to Improve Safety of Preparing and Administering Chemotherapy supported by the National Cancer Institute as well as private investors. 

Alliance & Collaborations
NCI grants and awards
Supporting Metrics or Evidence

Launched a multi-center research study funded by the National Cancer Institute (NCI) as part of a series of Small Business Innovation Research (SBIR) grants, the aim of this study is to demonstrate the improvements that Corvida’s technology could bring to the safe handling of hazardous drugs. 

Current Financing Needs

Raising $5M series B round

Current Timeline

First quarter 2015 510 applicartion. Approval Q 2 2015

Current Investors

Disclosed under NDA

IP Status

7 patents isued

15 PCT utility patents pending

Recent Milestones

Closed 2 rounds of financing and current 

Management Team Highlights

Corvida Medical is led by CEO, Kent Smith, MBA, who brings over 20 years of successful commercialization and leadership experience in the medical device start-up arena, to include Suros Surgical, which had a very successful exit, and in large corporations, such as American Hospital Supply and Baxter Healthcare.

 

Corvida Medical
Co-Founder & CEO 

Robin Smith United States

ORIG3N is a biotech company based in Boston, MA. The scientific mission is to deliver a disease-modeling platform targeting rare genetically inherited diseases. By advancing screening projects using iPSC-derived differentiated cells and rapidly delivering the resulting data to inform therapeutic decisions, ORIG3N will replace trial & error guess work of treating disease and enable longer, healthier lives. 

Website:
www.orig3n.com
Biotech Subsector
Medtech Subsector
Technology Overview
ORIG3N specializes in the generation of patient specific iPSC-derived cardiomyocytes, neurons, and hepatocytes. We have also built a unique iPSCs bank, called Life Capsule, with fully consented samples from patients with various neurodegenerative and cardiac diseases. Utilizing the diverse patient population from Life Capsule, we are able to provide patient and disease specific cell models.
Management Team Highlights
Successful repeat entrepreneurs, the founding team has 60+ years of experience in life science. Robin Smith, the CEO has 3 prior successful exits - the most recent two were VC backed and both sold to publicly traded companies; provided 24:1 return and 74%IRR to prior investors.
ORIG3N
CEO 

Kent Smith United States

Headquartered in the greater Iowa City area, Corvida Medical innovates intelligent technologies that are designed to represent the next generation of safe handling of hazardous drugs and excellence in design.  We address the problems inherent in current methods and develop smarter, simpler solutions to improve safety, productivity and quality for providers and patients. Our first technology, a novel new Closed System Transfer Device – the Halo™ — will be available in 2015.

Indication
Biotech Phase of Development
Medtech Phase of Development
Technology Overview

Corvida Medical is an emerging device company optimizing the safe handling of hazardous drugs, such as chemotherapeutics used to treat cancer patients. Millions of healthcare providers are at risk of exposure to hazardous drugs each year, resulting in adverse events such as cancers, reproductive toxicity, genetic mutations, etc. The company has developed anInnovative Device to Improve Safety of Preparing and Administering Chemotherapy supported by the National Cancer Institute as well as private investors. 

Alliance & Collaborations
NCI grants and awards
Supporting Metrics or Evidence

Launched a multi-center research study funded by the National Cancer Institute (NCI) as part of a series of Small Business Innovation Research (SBIR) grants, the aim of this study is to demonstrate the improvements that Corvida’s technology could bring to the safe handling of hazardous drugs. 

Current Financing Needs

Raising $5M series B round

Current Timeline

First quarter 2015 510 applicartion. Approval Q 2 2015

Current Investors

Disclosed under NDA

IP Status

7 patents isued

15 PCT utility patents pending

Recent Milestones

Closed 2 rounds of financing and current 

Management Team Highlights

Corvida Medical is led by CEO, Kent Smith, MBA, who brings over 20 years of successful commercialization and leadership experience in the medical device start-up arena, to include Suros Surgical, which had a very successful exit, and in large corporations, such as American Hospital Supply and Baxter Healthcare.

 

Corvida Medical
CEO 

Courtney Smith

Website:
www.hovione.com
Hovione
Director Business Development and Licensing 

Dr Daniel Smith United States

DELSIA is a "venture philanthropy" investment affilate of the research and advocacy foundation Autism Speaks. Our purpose is to transform lives by catalyzing the development and availability of innovative products.

DELSIA is a non-dilutive funding vehicle with the goal of improving outcomes for individuals with autism spectrum disorder (ASD). DELSIA aims to do this by enabling the translation of scientific breakthroughs and technological advances into products that improve health and quality of life for individuals with ASD and their families. 

Who and what do we invest in? DELSIA partners with for-profit companies to fund development activities necessary for delivering products that address the diverse unmet medical, behavioral health and quality of life needs of the autism community.

DELSIA accepts funding proposals from for-profit entities that include, but are not limited to:

• Entrepreneurs, start-up and small companies

• Life sciences, biotechnology and pharmaceutical companies

• Software, computer and electronic technology companies

Dr Daniel Smith
Delivering Scientific Innovation for Autism LLC
LinkedIn logo President 

Carl Soderstrom

Green Park & Golf Ventures (GPG) is a family office based in Dallas Texas. The firm was founded in 211 and is focused on healthcare companies. The firm makes seed venture and growth stage investments. The firm typically provides seed and Series A equity financing in the range of $1K to $1M per portfolio company. The firm generally acts as the lead investor and is open to invest in syndicates. The firm primarily invests in companies that are based in Texas but is open to opportunities across North America. The firm is actively seeking new investment opportunities.
Green Park & Golf Ventures
Founding Partner 

Chad Souvignier

RCT Ventures invests in early-stage life science companies including medical devices, drug discovery platforms, and research tools.

RCT Ventures
Managing Director 

Anna Spektor

Collaborative Drug Discovery
Customer Success Manager