Mr André de Fusco United States

Cynvenio has developed a new LiquidBiopsy technology to sequence the DNA of tumor cells isolated from peripheral blood. Key applications include longitudinal patient monitoring throughout the cancer care cycle, the detection of resistance mutations, and providing physicians with accurate molecular evidence to select the best targeted therapy for a given patient.

Cynvenio's technology can be accessed as a CLIA lab service, or  can be installed and operated inside hospital labs and cancer research centers. Cynvenio's lab has been CLIA certified since 2013 and LiquidBiopsy system deployments began in the second half of 2014.

Website:
www.cynvenio.com
Year Founded
2008
Biotech Subsector
Medtech Subsector
Biotech Phase of Development
Technology Overview
Sequencing tumor cells from whole blood
Alliance & Collaborations
Yes, US and International
Supporting Metrics or Evidence
CLIA/CAP accreditation, validations completed, generating revenue
Current Financing Needs
$15M
Current Timeline
Series C raise to scale commercial
Current Investors
Privately funded
IP Status
Core IP has issued
Recent Milestones
4 US deployments, 2 strategics
Management Team Highlights
Amgen, Nortel, Harvard, UCLA, McKinsey
Cynvenio Biosystems, Inc.
LinkedIn logo CEO 

Koen De Lombaert United States

Yuzu Labs, based in Silicon Valley, is a research startup that aims to make clinical, behavioral, and social research more accessible, easier, faster, and cheaper. We've recently launched a private beta of our initial product named StudyPages. Researchers can use this web application to quickly set up a dedicated webpage for their studies, share with target communities, and track signups. Please visit the site to learn more: https://studypages.com
Year Founded
2014
Service Provider Type
Koen De Lombaert
Yuzu Labs
LinkedIn logo Co-Founder 
BIO

Koen holds a MD (Catholic University Leuven, Belgium) and a MBA (Johns Hopkins University) and worked in lifesciences, bioinformatics, business development, marketing, and product management in academia, startups, and at Roche Pharmaceuticals. Koen enjoys technology and UX design and builds wireframes for new product ideas. His passion for science and entrepreneurshipmade him move stepwise from Belgium to the West and he calls Silicon Valley now his new home.

John De Michele United States

The HudsonAlpha Institute for Biotechnology

 

The HudsonAlpha Institute for Biotechnology is a Genomic focused Institute located on a 152-acre bio-medical research campus in Huntsville, Alabama whose mission is to translate scientific breakthroughs in the laboratory into real-world benefits that have a profound impact on people’s lives.

 

HudsonAlpha BioVentures Philanthropic Fund

•       Specific Philanthropic Fund - part of the HudsonAlpha Foundation a tax-exempt, 501(c) 3 non-profit organization.

•       All investments to the Fund are tax-deductible

•       Fund goal is $50 million

•       Targeted toward donors seeking to make a long-term impact in human health and make a difference for thousands, even millions, of people suffering from serious disease.

 

Option 1

HudsonAlpha Foundation invests funds in new or established companies and scientific discoveries. Foundation will have an equity stake and receive a ROI, as companies are successful. The return is reinvested into other companies and HudsonAlpha to further its mission and goals – the multiplier effect.

Option 2

HudsonAlpha Foundation will fund promising intellectual property emanating from HudsonAlpha laboratories.

Option 3

HudsonAlpha Foundation provides grant funding to companies who are relocating to or expanding on the HudsonAlpha campus.

 

All investors/donors will have an opportunity to invest in the future in any and all companies and will be informed regularly on the progress of these companies

Year Founded
2008
Biotech Subsector
Management Team Highlights
Richard M. Meyers Ph.D President and Director of Science •Internationally recognized thought leader in genomics and genetics •Leads scientific collaborations in 18 countries with over 700 researchers and clinicians •Scientific expertise in cancer research including breast, kidney, prostate; neurological disorders including ALS, Parkinson’s disease; psychiatric disorders including schizophrenia, bipolar disorder and major depression. •Former Chair of the Department of Genetics at Stanford University and Director of the Stanford Human Genome Center •Dr. Myers and his lab contributed 11% of the data in the Human Genome Project’s efforts to sequence the first human genome. •Ph.D. in Biochemistry, University of California Berkeley •Performed doctoral work at Harvard University with Dr. Tom Maniatis
HudsonAlpha Institute for Biotechnology
Vice President for Advancement 
BIO
JohnDeMicheleJohn De Michele

Vice President for Advancement

John De Michele came to HudsonAlpha in June 2014 from San Diego, bringing with him 30 years of fundraising leadership and nonprofit executive experience. His diverse background ranges from Tufts University to Northwestern University Medical Center Foundation, from the National Jewish Medical and Research Center to the San Diego Symphony, where he mobilized the largest single gift in its history: $125 million. De Michele understands the challenges facing nonprofit leaders today and acts strategically, and tirelessly on behalf of the Institute.

Christopher de Souza

Broadview Ventures is a Philanthropy Venture firm that was established by the Leducq Family Trust in 28 and dedicated to accelerating the translation of new and innovative programs in the CV and stroke areas. The firm is based out of Boston MA but is geographically agnostic in its investing. The firm makes equity and convertible note investments of approximately $1 million into companies that are targeting cardiovascular and neurovascular diseases. The firm invests in privately held companies at both the seed and venture stage and is currently invests in 4-5 companies per year. The firm operates under an evergreen structure and is constantly seeking new investment opportunities. While the firm will consider investments around the globe Broadview is keen to add companies based in Europe to its portfolio. Broadview has previously invested in the US Europe and Israel.
Broadview Ventures
Director 

Rosamond Deegan

Small biotechnology companies are developing half of all future medicines, some of which may not reach patients due to lack of funding from traditional investors.

Although health-related charities received more than $31B in contributions in 2013, many of the charities which support research do not work with for-profit biotech companies. They predominantly fund academic and non-profit institutions which typically conduct early research and discover around 10% of new medicines (for-profit companies discover the remaining 90%).

Impatient is a new kind of health-related charity. We will only fund medical trials with small biotech companies.  

Our scientific advisors will select promising, unfunded, medical treatments. You choose which treatment to support and 100% of your donation is spent on testing.

If the treatment is successful, 100% of the future royalty that Impatient receives from the biotech company will support access to new medicines for people who cannot afford them.  

Capital Structure Preference
Investment Stage Preference
Impatient
Acting CEO 

Ron Demuth

Torrey Pines Investment (TPI) was founded in 22 and is based in San Diego CA. The firm has raised two funds and also invests in drug development via a partnership with BioMotiv. TPI makes venture-stage minority equity investments and prefers act as a co-investor but also leads rounds on occasion. The firm invests internationally.

Torrey Pines Investment
President 

Steve DeNelsky United States

Life Sciences Alternative Funding (LSAF) founded in 213 is a direct investment firm based in White Plains New York. The firm focuses exclusively on providing debt capital for commercial-stage medical technology companies. The firm can allocate between USD 1M-5M per investment. The firm looks to provide flexible ?tailor-made? financing solution to companies. The firm can invest globally and is currently seeking new investment opportunities.

Life Sciences Alternative Funding
President 

Eric Desai United States

Greenhouse Capital Partner is a venture capital firm that was founded in 2006 and is based in Sausalito, California. The firm selectively makes equity investments into life science companies in seed stage and series A financing round, but it also provides growth equity to highly capital efficient companies that can achieve cash flow break-even within two years. The typical investment size ranges from $0.25 million to $2 million.The firm focuses on investments in US based companies.

Greenhouse Capital Partners
Principal